Does the Pre-operative Use of Probiotic Prevent Ileus In Patients with Colorectal Cancer After Surgery ? A Randomized, Double- Blind, Placebo-Controlled Trial.

Not Applicable

Completed

• Conditions: Ileus in patients with colrectal cancer after surgery; Oral and Gastrointestinal - Normal oral and gastrointestinal development and function; Cancer - Bowel - Back passage (rectum) or large bowel (colon)

• Registration Number: ACTRN12615000545561
• Lead Sponsor: niversity of Malaya

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2015-05-28
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

i) The diagnosis of colorectal cancer was confirmed by biopsy and histiological test

ii) Patients whose biopsy confirmed colorectal cancer and scheduled to undergo colorectal surgery

iii) Age 18 years or above

Exclusion Criteria

i.Acute intestinal obstruction
ii.Age <18 years
iii.Clinically significant immunodeficiency
iv.Evidence of infection
v.Undergoing emergency operation
vi.Gastric outlet obstruction
vii.Unable tolerate orally
viii.Pregnancy or lactating.
ix.Known lactose intolerance
x.Unstable psychological conditions or having psychic disorder.
xi.Severe medical illness such as end-stage renal failure, liver cirrhosis, advanced connective tissue disease, chronic congestive heart failure.
xii.Acute shock.
xiii.History of pre-existing arterial disease (recent myocardial infraction, stroke or TIA) and unstable angina pectoris.
xiv.Regular ingestion of any probiotics within 1 week prior to recruitment.

Study & Design

• Study Type: Interventional
• Study Design: Not specified