ED50 of Dexmedetomidine to Prevent Emergence Agitation in Children

Phase 4

• Conditions: Agitation
• Interventions: Drug: Dexmedetomidine

• Registration Number: NCT01374737
• Lead Sponsor: Seoul National University Hospital

Brief Summary

There are several recommended doses of dexmedetomidine for prevention of emergence agitation in children. In this study, the investigators examine ED50 in prevention of emergence agitation after tonsillectomy or adenoidectomy in children.

Detailed Description

To investigate ED50, Dixon's up and down method will be used.

Study Timeline

• Status Verified: 2011-06
• Study Start: 2011-06
• Study First Submitted: 2011-06-09
• Study First Submitted QC: 2011-06-15
• Last Update Submitted: 2011-06-15
• Study First Posted: 2011-06-16
• Last Update Posted: 2011-06-16
• Primary Completion: 2011-12
• Study Completion: 2012-02

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 25

Inclusion Criteria

• tonsillectomy or adenoidectomy

Exclusion Criteria

• recent URI

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
dexmedetomidine, children	Dexmedetomidine	-

Primary Outcome Measures

Name	Time	Method
agitation	30 minutes

Secondary Outcome Measures

Name	Time	Method
pain	30 minutes

Trial Locations

Locations (1)

SNUH; 🇰🇷 Seoul, Korea, Republic of