Value of arterial spin labeling in the clinical imaging protocol of pediatric brain tumors

Completed

• Conditions: brain tumor; neuro-oncology; 10029211

• Registration Number: NL-OMON35442
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 120

Inclusion Criteria

- 0 to 18 years of age
- appointed to undergo a MRI-scan (all cranial MRI-scans during follow-up will be included)
- suspected, diagnosed or (previously) treated brain tumor (i.e. cranial central nervous system (CNS)-tumor)

Exclusion Criteria

- patients who do not meet the specific inclusion criteria;
- contraindications for MRI, such as claustrophobia or the presence of metal in the body;
- inability of parents/legal guardians or patients themselves, if older than 12 years of age, to provide informed consent;
- refusal by the child of any age before or during the imaging procedure

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>baseline cerebral blood flow, tumor World Health Organization malignancy grade<br /><br>diagnosed by histology.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>cerebral blood flow at follow-up; results of the clinical scans at baseline and<br /><br>follow-up</p><br>