Effect of consumption of probiotic containing Saccharomyces boulardii to extended-spectrum beta-lactamases (ESBL)-producing Escherichia coli in carrier persons: A randomized controlled trial
Phase 3
Completed
- Conditions
- ESBL E. coli carriers
- Registration Number
- TCTR20180313002
- Lead Sponsor
- Department of Microbiology, Phramongkutklao College of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 68
Inclusion Criteria
- living in Phrapleng community, Sa Keaw Province, Thailand
- age over 18 years old
- Stool culture positive for ESBL E. coli
- consent to participate in the research
Exclusion Criteria
- Immunocompromised host eg. AIDs, immunosuppressant users etc.
- consummation of active microbiota food eg. curd, yogurt etc. at the time of intervention carry (3 weeks)
- taking antibiotics that effect ESBL bacteria; Carbapenems, Beta-lactamase inhibitor and Aminoglycosides at the time of intervention carry (3 weeks)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method prevalence of ESBL E. coli carriers after intervention in both groups of participants before and after intervention Screening test by stool culture on selective ESBL agar, confirmatory test by MALDI-TOF and combine
- Secondary Outcome Measures
Name Time Method /A N/A N/A