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Pathophysiological study on mild verbal cognitive impairment with left temporal lobe degeneration using PET imaging of amyloid and tau depositio

Not Applicable
Recruiting
Conditions
primary progressive aphasia
Registration Number
JPRN-UMIN000046538
Lead Sponsor
Kobe City Medical Center General Hospital
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
2
Inclusion Criteria

Not provided

Exclusion Criteria

1. Suspected of vascular dementia. 2. Cognitive impairment by suspected causes other than neurodegenerative disorders. 3. Suspected of psychiatric disorders such as schizophrenia and depression. 4. Unable to lie on bed for 60min. 5. Extreme claustrophobia. 6. Unable to undergo MRI scan. 7. Anticipatorily unable to undergo all the psychological tests of this study. 8. Possibility of pregnancy. 9. No capacity to consent, for example, due to dementia. 10. Inappropriate for enrollment as determined by principal investigator.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
presence/absence of amyloid deposition evaluated by PET
Secondary Outcome Measures
NameTimeMethod
PET images of amyloid, tau and glucose metabolism. Language and semantic cognitive function.
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