Head Elevation During Pre-oxygenation Can Delay Desaturation Time in Indonesian Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 56
- 试验地点
- 1
- 主要终点
- Desaturation time
研究概览
简要总结
This study is a randomized-controlled trial study comparing the association between several degree of head elevation and conventional position during pre-oxygenation to desaturation time in patients undergo endotracheal intubation with general anesthesia
详细描述
Preoxygenation anesthesia induction is an important part of airway management to reduce the risk of hypoxemia when the patient is apneic. The effectivity of preoxygenation is influenced by several things such as patient's head position. This study aimed to compare preoxygenation with head elevation 20°, 30° and 45° and conventional position to the time of desaturation before endotracheal intubation in patients undergoing general anesthesia. This was a randomized clinical trial of 56 patients, divided into four groups (conventional or 0° head elevation group, 20° head elevation group, 30° head elevation and 45° head elevation group). All subject was preoxygenated for 3 minutes with 100% oxygen. Induction of anesthesia was started with fentanyl, propofol, followed by rocuronium after the patient lost consciousness. Time was recorded from the start of induction until the oxygen saturation showed 93% or a time limit of 5 minutes. There was a significant difference in mean desaturation time among the four groups (p = 0.011). The most significant different was in 45o head elevation group (p < 0.05). . In patients undergoing general anesthesia, pre-oxygenation with head elevation 20°, 30° and 45° slows down the time for desaturation before endotracheal intubation compared to the conventional position. The 45° head elevation has the best result.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
盲法说明
The care provider and investigator were not blinded.
入排标准
- 年龄范围
- 18 Years 至 60 Years(Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •undergo endotracheal intubation with general anesthesia for elective surgery
- •aged 18-60 years old
- •ASA physical status 1-2 preoperatively
排除标准
- •Patients with difficult airway, cardiopulmonary disease, anemia, grade II obesity, pregnant, history of hypersensitivity to induction agents
- •Patients did not give consent to follow the study
研究组 & 干预措施
Control
Patient positioned in supine conventional position
干预措施: Supine position (Procedure)
20 degree head elevation
Patient positioned in 20 degree head elevation position
干预措施: 20 degree head elevation position (Procedure)
30 degree head elevation
Patient positioned in 30 degree head elevation position
干预措施: 30 degree head elevation position (Procedure)
45 degree head elevation
Patient positioned in 45 degree head elevation position
干预措施: 45 degree head elevation position (Procedure)
结局指标
主要结局
Desaturation time
时间窗: Right after induction until reach oxygen saturation 93% or 5 minutes time limit
Time was recorded from the start of induction until the oxygen saturation showed 93% or a time limit of 5 minutes
次要结局
未报告次要终点
研究者
Ratna Farida Soenarto
Principal Investigator
Indonesia University
