Comparison of Volatile Anesthetics on Cerebral Oxygenation During Controlled Hypotension
- Registration Number
- NCT02834845
- Lead Sponsor
- Ufuk University
- Brief Summary
Controlled hypotension is a preferred method for reducing surgical bleeding during septoplasty operations however, the level of hypotension and bradycardia should not disrupt cerebral oxygenation. On this account, the investigators aim to investigate the effects of different volatile anesthetics combined with a short-acting opioid on cerebral oxygenation during controlled hypotension using near infrared spectroscopy.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 95
Inclusion Criteria
- Patients in American Society of Anesthesiology (ASA) classification I and II
- Patients undergoing elective septoplasty operation
Exclusion Criteria
- Patients in ASA classification III and higher
- Emergency surgery
- Patients in New York Heart Association classification III-IV
- Patients with known allergy to drugs used in the study
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Sevoflurane Sevoflurane - Desflurane Desflurane -
- Primary Outcome Measures
Name Time Method Cerebral oxygen saturation as measured by Near Infrared Spectroscopy Duration of surgery The effect of sevoflurane and desflurane on NIRS values
- Secondary Outcome Measures
Name Time Method The effect of anesthetics on hemodynamic variables Duration of surgery The effects of sevoflurane and desflurane on bispectral index
Total remifentanil consumption as measured in micrograms Duration of surgery
Trial Locations
- Locations (1)
Ufuk University Hospital
🇹🇷Ankara, Turkey