The Precision and Arm-to-Arm Variation of Mechanomyography and Acceleromyography for Monitoring of Neuromuscular Block
Completed
- Conditions
- Neuromuscular Blockade
- Interventions
- Device: TOF-Watch SX (neuromuscular monitor)
- Registration Number
- NCT00472121
- Lead Sponsor
- Rigshospitalet, Denmark
- Brief Summary
The purpose of the study is the examine the precision of acceleromyography and mechanomyography during recovery from a neuromuscular blocking agent and to examine whether there is any difference in monitoring block at the dominant or non-dominant arm. Our hypothesis is that there is no significant difference in neither the precision nor the level of block in the contralateral arms.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
- ASA I-III
- General anesthesia >1 hour
- Surgery in supine position w. possibility of monitoring the neuromuscular block at both arms (n. ulnaris stimulation/thumb response)
- Written informed content
Exclusion Criteria
- Neuromuscular disorders, hepatic and renal dysfunction
- Medication expected to interfere with the neuromuscular blocking agent
- Allergy to any medication used during anaesthesia
- Body weight less or exceeding 20% of ideal body weight
- Pregnancy or breastfeeding
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description 2: MMG TOF-Watch SX (neuromuscular monitor) - 1: AMG TOF-Watch SX (neuromuscular monitor) -
- Primary Outcome Measures
Name Time Method Precision at the contralateral arms using the average residual coefficient of variation over subsequent linear regressions (detrending) over time
- Secondary Outcome Measures
Name Time Method Bias and limits of agreement between control TOF, reappearance of T1, T2, T3, T4 Time to TOF 0.9 and 1.0 with and without normalization Time to stable T1 and stable TOF T1 height at reappearance of T1-T4 Interval 25-75% Time to T1=25%
Trial Locations
- Locations (1)
Dep. of Anaesthesia
🇩🇰Copenhagen, Denmark