nderstanding how critical illness and liver disease affect blood clotting
Not Applicable
- Conditions
- iver disease, critical illness, platelet functionHaematological Disorders
- Registration Number
- ISRCTN11565046
- Lead Sponsor
- Royal Berkshire NHS Foundation Trust
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Ongoing
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
Current participant inclusion criteria as of 24/05/2024:
1. Admitted to ICU at the Royal Berkshire Hospital
2. Aged 18 years old and above
3. Evidence of established liver disease, or acute liver dysfunction related to underlying illness, as determined by the clinicians caring for the patient at the time of eligibility assessment.
Previous participant inclusion criteria:
1. Known liver disease or
2. Acute liver dysfunction
Exclusion Criteria
1. Patients on P2Y12 inhibitors (including clopidogrel, ticagrelor and prasugrel)
2. Patients on treatment-dose anticoagulation, including warfarin or novel anticoagulant drugs
3. Patients under 18 years of age
4. Active or recent malignancy (< 1 year) or on active treatment
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method