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An Open-Label Multicentre Long-Term Extension Study of Etanercept for Ankylosing Spondylitis

Phase 4
Completed
Conditions
Ankylosing Spondylitis
Registration Number
NCT00444340
Lead Sponsor
Wyeth is now a wholly owned subsidiary of Pfizer
Brief Summary

This study is an extension trial of 0881A3-312-EU and is designed to provide information on the safety and efficacy of etanercept in patients with ankylosing spondylitis for up to 3 additional years.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
70
Inclusion Criteria
  • Completed study 0881A3-312-EU
  • Agreeable to utilize medically acceptable form of contraception
  • Able to reconstitute and self-inject or have a designee
Exclusion Criteria
  • Withdrawn from study 0881A3-312-EU
  • Abnormal hematology or chemistry profiles
  • Clinically relevant medical conditions including: congestive heart failure, multiple sclerosis or other central demyelinating diseases, blood dyscrasias, cancer or serious infection

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Primary Outcome Measures
NameTimeMethod
To evaluate the long-term safety of etanercept in adults with ankylosing spondylitis who have completed study 0881A3-312-EU.
Secondary Outcome Measures
NameTimeMethod
To assess the long-term clinical efficacy of etanercept in these study subjects.
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