Dexamethasone, Paracetamol and Ketorolac combination for pain relief and opioid sparing effects in total laparoscopic hysterectomy
Not Applicable
Completed
- Conditions
- Health Condition 1: N859- Noninflammatory disorder of uterus, unspecified
- Registration Number
- CTRI/2022/04/041624
- Lead Sponsor
- Parin Lalwani
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 100
Inclusion Criteria
Patients of ASA physical status I and II posted for elective total laparoscopic hysterectomy
Exclusion Criteria
1.Patient refusal
2.Known allergy to the drugs
3.History of chronic analgesic or steroid consumption
4.History of gastric or duodenal ulcer
5.BMI >30
6.History of asthma
7.History of diabetes mellitus
8.History of endometriosis
9.Chronic alcoholism
10.Liver and/or kidney dysfunction
11.Limitations in understanding use of PCA pump
12.Duration of surgery >2 hrs / converted to open surger
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Total intravenous Patient controlled analgesia(PCA) fentanyl consumption in the first 24 hours postoperativelyTimepoint: 24 hours postoperatively
- Secondary Outcome Measures
Name Time Method 1.Time for first analgesic requirementTimepoint: 24 hours postoperatively;2.Post operative pain scores at rest and during movement 0min 15min 30min 1,2,4,8,12 and 24 hours postoperatively <br/ ><br> <br/ ><br>Timepoint: 0min, 15min, 30min , 1,2,4,8,12,24 hours;Post operative nausea and vomitingTimepoint: 0min, 15min, 30min , 1,2,4,8,12,24 hours;Wound healingTimepoint: 7 days postoperatively