The Effect of Intravenous Nalbuphine on PONV With Intrathecal Morphine in Abdominoplasty.

Not Applicable

• Conditions: Abdominal Obesity
• Interventions: Drug: Intrathecal Morphine; Drug: Intrathecal Morphine + Intravenous Nalbuphine

• Registration Number: NCT03786562
• Lead Sponsor: Assiut University

Brief Summary

How effectively intravenous nalbuphine can reduce the incidence of PONV after intrathecal administration of morphine in abdominoplastic surgery.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2018-12-19
• Study First Submitted QC: 2018-12-20
• Study First Posted: 2018-12-26
• Status Verified: 2019-03
• Study Start: 2019-03-08
• Primary Completion: 2020-03
• Last Update Submitted: 2020-03-13
• Last Update Posted: 2020-03-16
• Study Completion: 2020-09

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Female
• Target Recruitment: 80

Inclusion Criteria

• Patients undergoing abdominoplasty under spinal anesthesia
• American Society of Anesthesiologists (ASA) class I and II.

Exclusion Criteria

• allergy to local anesthetics
• bleeding diatheses
• local infection or sepsis

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Placebo group	Intrathecal Morphine	-
Nalbuphine group	Intrathecal Morphine + Intravenous Nalbuphine	-

Primary Outcome Measures

Name	Time	Method
postoperative nausea and vomiting	24 hours	A verbal descriptive scale (VDS) was used to assess the severity of PONV. ( no nausea=0, severe nausea= 10); by postoperative nausea and vomiting scale which range (o no nasuea to 10 sever vomating).; A verbal descriptive scale (VDS) was used to assess the severity of PONV .

Secondary Outcome Measures

Name	Time	Method
postoperative pain and puririts.	24 hours	Visual analogue scale (VAS) pain scores (no pain = 0, worst possible pain = 10).

Trial Locations

Locations (1)

Assiut University Hospital; 🇪🇬 Assiut, Egypt