Analgesic effect of combining Midazolam, Morphine and Diphenhydramine for acute postoperative pain management, A comparative study
Phase 3
- Conditions
- postoperative pain.Injury of long flexor muscle, fascia and tendon of thumb at wrist and hand levelS66.0
- Registration Number
- IRCT20130304012695N2
- Lead Sponsor
- Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 66
Inclusion Criteria
Patients are extubated after surgery and recover. In recovery, patients were evaluated based on VAS or Richmond criteria, and if they had a VAS> 4 score or Richmond +2 and above, they entered the study and were randomly assigned to one of the two groups.
Exclusion Criteria
opioids addiction, underlying ischemic cardiac diseases, renal function and liver function diseases, history of allergic reaction to any of the medications used, and use of any antiemetic and antipsychotic medications, PONV and glaucoma.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The effect of the drug combination of midazolam, diphenhydramine and morphine on pain relief. Timepoint: In 5, 10, 15, 30 minutes after the operation, the severity pain was measured. Method of measurement: visual analog scal.
- Secondary Outcome Measures
Name Time Method Patients' agitation evaluation. Timepoint: In 5, 10, 15 and 30 minutes after surgery. Method of measurement: richmond agitation scale.