Evaluation of the effect of vitamin D consumption on the AntiTPO

Phase 2

Recruiting

Conditions: Autoimmune Hypothyroidism.
Autoimmune thyroiditis
E06.3

Registration Number: IRCT20210802052054N1

Lead Sponsor: Tabriz University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: All

Target Recruitment: 128

Inclusion Criteria

Patients of both sexes who have AntiTPO positive and their disease is approved by an endocrinologist and are in the age range of 18 to 65 years.

Exclusion Criteria

Patients who have evidence of any disease that affects the balance of the immune system, such as those with type 1 diabetes, multiple sclerosis, inflammatory bowel disease, and other autoimmune diseases.
Patients with impaired liver enzyme function
Malnourished patients
Patients with a BMI of less than 18 or more than 40.
Patients with hyperthyroidism and decreased TSH levels.

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Serum levels of Anti TPO before and after taking vitamin D. Timepoint: Anti TPO levels are measured before the intervention and 3 and 6 months after the start of vitamin D intake. Method of measurement: After starting the study, blood samples are taken from the patients and the patients' serum is removed. Using special Anti TPO kits, the level of Anti TPO is measured by ELISA and the effect of vitamin D level on the level of Anti TPO in the serum is examined.

Secondary Outcome Measures

Name	Time	Method
Evaluation of serum vitamin D levels in patients with Anti TPO positive. Timepoint: Serum vitamin D levels are measured before the intervention and 3 and 6 months after the start of vitamin D intake. Method of measurement: After starting the study, blood samples are taken from the patients and the patients' serum is removed. Using special Vitamin D kits, the level of vitamin D is measured by ELISA.