Comparison the Effect of Adding Two Different Doses of Dexmedetomidine to Ropivacaine on Pain After Cesarean Sectio

Phase 3

Recruiting

• Conditions: Postoperative Pain after Cesarean Section, The effect of ropivacaine and dexmedetomidine drugs.

• Registration Number: IRCT20221122056579N1
• Lead Sponsor: Esfahan University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 7 February 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: 90

Inclusion Criteria

Patients who are candidates for cesarean surgery (for the first time)
Performing cesarean surgery under spinal anesthesia
ASA I&II (American society of anesthesiologists)

Exclusion Criteria

Patients with a History of Drug Allergy (Dexmedetomidine And Ropivacaine)
Patients with a History of Tobacco and Opioid Addiction
Patients with Psychological Problems
Obese Patients Weighing More Than 100 kg
Patients with Inability to Express Pain Score
Suffering from Intracranial Hypertension
Twin Pregnancy and Above
Previous Abdominal and Pelvic Surgeries
Uncontrollable Underlying Disease (ASA3 and higher)

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pain after cesarean section based on Visual Analogue Scale. Timepoint: Pain at baseline (before spinal anesthesia) and then every 15 minutes during recovery and after that at 2, 4, 6, 12, 24 hours after surgery in the ward. Method of measurement: Visual Analogue Scale, It is evaluated based on a score from 0 (no pain) to 10 (severe pain).

Secondary Outcome Measures

Name	Time	Method
The amount of additional analgesic. Timepoint: If the patient's VAS is more than 4 cm, diclofenac sodium suppository 100 mg is used to relieve pain. Method of measurement: The number of diclofenac sodium suppositories 100 mg.;The first time to receive analgesics. Timepoint: If the patient's VAS is more than 4 cm, diclofenac sodium suppository 100 mg is used to relieve pain. Method of measurement: Number of minutes after surgery.;• The incidence of side effects include: nausea and vomiting, chills, hallucinations, hypotension (<30% of baseline), bradycardia (<60), hypertension and tachycardia (increase of more than 30% compared to baseline), Respiratory depression (< 10 times per minute). Timepoint: After recovery until discharge. Method of measurement: has/doesn't have.;Patient satisfaction based on VAS. Timepoint: in hours 2, 4, 6, 12, 24 after entering the ward. Method of measurement: Visual Analogue Scale.