A Study on the Comparison of Effects in Lower Body Surgeries using A Local Anesthetic with two different Adjuvants

Not yet recruiting

Conditions: Medical and Surgical,

Registration Number: CTRI/2023/06/053534

Lead Sponsor: Gulbarga institute of medical sciences

Brief Summary: This study is mainly aiming to study the efficacy of two different drugs .Here Buprenorphine is already an established drug where as Dexmedetomidine is a newly introduced drug.This is first time that comparison of these two drugs are being used in Epidural anaesthsia for lower limb surgeries.So hoping this study will be helpful for mankind with good outcomes

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 60

Inclusion Criteria

American Society of Anaesthesiologists status I and II Adult patients of age group between 18-60 years Patients undergoing for elective lower limb Orthopedic surgeries BMI between 18.5kg/m2 to 29.9kg/m2.

Exclusion Criteria

Any bleeding disorders and patients on anticoagulants Neurological and musculoskeletal diseases Local infection at the epidural site Allergic history to local anaesthetics in previous surgeries Pregnant females.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To compare the duration of analgesia in both the groups.	Onset of sensory and motor blockade to be assessed every minute after giving the drug. \| Duration of sensory and motor blockade to be assessed every 30 minutes after onset of blockade. \| Duration of analgesia to be assessed starting 2-3 hours after administration of drug till the patient complaints of pain
To compare the onset and duration of sensory and motor blockade after adding Dexmedetomidine and Buprenorphine as adjuvant to Ropivacaine in epidural anaesthesia for lower limb orthopaedic surgeries.	Onset of sensory and motor blockade to be assessed every minute after giving the drug. \| Duration of sensory and motor blockade to be assessed every 30 minutes after onset of blockade. \| Duration of analgesia to be assessed starting 2-3 hours after administration of drug till the patient complaints of pain

Secondary Outcome Measures

Name	Time	Method
1.To study the haemodynamic parameters in both groups	2.To study the adverse effects in both groups.

Trial Locations

Locations (1): Gulbarga Institute of Medical Sciences
🇮🇳
Gulbarga, KARNATAKA, India
Gulbarga Institute of Medical Sciences
🇮🇳Gulbarga, KARNATAKA, India
Aswin M S
Principal investigator
09539059561
thegr8ams@gmail.com