Mast Cells and Its Proteases in COPD

Not Applicable

Recruiting

• Conditions: COPD Exacerbation
• Interventions: Other: Biopsy

• Registration Number: NCT06392334
• Lead Sponsor: Voronezh N.N. Burdenko State Medical Academy

Brief Summary

Mast cells proteases such as chymase and tryptase will be studied in the tissue of small and large airways in COPD patients

Detailed Description

Not available

Study Timeline

• Study Start: 2019-01-29
• Study First Submitted: 2019-09-22
• Status Verified: 2024-04
• Study First Submitted QC: 2024-04-26
• Last Update Submitted: 2024-04-26
• Study First Posted: 2024-04-30
• Last Update Posted: 2024-04-30
• Primary Completion: 2025-08-30
• Study Completion: 2025-09-30

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• COPD patients

Exclusion Criteria

Other lung diseases, tumors, pregnancy

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Biopsy	Biopsy	Biopsy of lung tissue will be done

Primary Outcome Measures

Name	Time	Method
Number of mast cells in COPD lung tissue	up to 10 -12 months	Assesment of mast cells in lung tissue in COPD patients

Trial Locations

Locations (1)

Voronezh State Medical University; 🇷🇺 Voronezh, Russian Federation