Food and the Brain

Completed

• Conditions: Binge Eating

• Registration Number: NCT02743000
• Lead Sponsor: Stanford University

Brief Summary

The proposed study will examine the role of reward and emotion in women with and without a history of binge eating. It is important to understand how the brain responds to reward and emotion in binge eating in order to identify different pathways toward binge eating and provide individualized targets for treatment. This is particularly important in light of the fact that for many patients, the current treatments for binge eating are not effective.

Detailed Description

Not available

Study Timeline

• Study Start: 2016-01
• Study First Submitted: 2016-04-12
• Study First Submitted QC: 2016-04-13
• Study First Posted: 2016-04-19
• Primary Completion: 2020-04
• Study Completion: 2020-04
• Status Verified: 2020-10
• Last Update Submitted: 2020-10-19
• Last Update Posted: 2020-10-20

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 83

Inclusion Criteria

• Female
• Ages 18-35
• with or without current binge eating behaviors

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Exclusion Criteria

• Any contraindication for MRI (orthodontia, vascular stents, metallic ear tubes, metal implants, piercings, etc).
• substance abuse
• traumatic brain injury
• BMI < 18.5
• pregnant women

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Brain activity during rest	Baseline	Functional magnetic resonance imaging will be used to measure brain activity at rest and connectivity between brain regions will be examined.
Brain activity during emotion conflict	Baseline	Functional magnetic resonance imaging will be used to measure brain activity during a task where participants respond to images of faces with emotional expressions overlaid with an emotion word written in text. We will focus on brain response during this task when emotion face vs word are in conflict.
Brain activity during monetary wins and losses	Baseline	Functional magnetic resonance imaging will be used to measure brain activity during a game where participants can win or lose money if they respond to a shape on the computer screen. Brain response during wins and losses will be examined.

Trial Locations

Locations (1)

Stanford University, Department of Psychiatry; 🇺🇸 Stanford, California, United States