Antispastic effect of Transcranial Magnetic Stimulation in Multiple Sclerosis

Not Applicable

• Conditions: Muscle Spasticity; C10.114.375.500

• Registration Number: RBR-2crspbc
• Lead Sponsor: niversidade Nove de Julho

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2023-07-11
• Last Update Posted: 26 July 2023
• Study Completion: 2023-08-31

Recruitment & Eligibility

• Status: Recruitment completed
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

over 18 years old; left lateral hemispheric dominance; confirmed diagnosis of multiple sclerosis; who present grade 3 spasticity according to the ashworth scale; the subtypes (remitting relapsing, primary progressive and secondary progressive); who have motor evoked potential for quadriceps

Exclusion Criteria

Application of phenol; botox or other procedures that interfere with quadriceps muscle tone within a period equal to or less than 6 months; Fracture or recent surgeries in lower limbs; Contracture or ankle deformity; History of seizures or refractory epilepsy; brain metallic implants; brain tumors or skin lesion at the application site

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
It is expected to find a better response for the high frequency protocol, verifying through the ashworth scale and the motor evoked potential the decrease in spasticity at the end of the study.

Secondary Outcome Measures

Name	Time	Method
For the secondary outcome, it is expected to find a better motor evoked potential response in individuals with multiple sclerosis after the application of the high frequency protocol with transcranial magnetic stimulation.