Using of Injectable Platelet Rich Fibrin on Filling the Gap of Immediate Dental Implant

Not Applicable

Completed

• Conditions: Bone Loss
• Interventions: Other: injectable platelet rich fibrin

• Registration Number: NCT04298294
• Lead Sponsor: Ain Shams University

Brief Summary

The effect of using of i-PRF (injectable platelet rich fibrin) on filling the gap of immediate dental implant in the esthetic zone

Detailed Description

Grouping the samples: (sixteen patients was recruited from the outpatient clinic of Oral Medicine, Periodontology, Diagnosis and Radiology Department, Faculty of Dentistry, Ain Shams University).

The sixteen patients assigned to group 1 or group 2 will be randomly allocated using flip of a coin into one of the 2 treatment modalities.

Primary objective:

Radiograhic evaluation of the effect of i-PRF on filling the buccal gap distance between the immediately placed dental implant and the surrounding bone.

Secondary objective:

Esthetic evaluation of the effect of i-PRF on the soft tissue around immediately placed dental implant.

Study Timeline

• Study Start: 2018-02-16
• Primary Completion: 2019-10-01
• Study Completion: 2019-12-01
• Study First Submitted: 2020-02-29
• Status Verified: 2020-03
• Study First Submitted QC: 2020-03-04
• Last Update Submitted: 2020-03-04
• Study First Posted: 2020-03-06
• Last Update Posted: 2020-03-06

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 16

Inclusion Criteria

• Healthy adult patient.

• Age from 20-50 years old

• Patients must be free of any systemic disease which could influence the surgical procedure.

• Tooth involved in the esthetic zone.

• Sufficient hard and soft tissue volume in vertical and buccolingual 6. Natural teeth adjacent to the involved tooth were required to be free from infection.

• Controlled oral hygiene.

• Indication for tooth extraction included;

  • Endodontic failures
  • Untreatable caries> Non- restorable teeth
  • Vertical root fracture
  • Remaining roots

• The decision to proceed with the implant placement was made after tooth extraction and probing of the extraction socket which revealed:

  • The presence of intact facial bone.
  • Compliance with all requirements in the study and signing the informed consent.

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Exclusion Criteria

• Patient had surgeries in the same site during the last 6 months prior to the surgery.
• Severe vertical bone loss (socket type lll or type lV).
• Presence of acute dento-alveolar infection or periodontal affected of involved tooth.
• Pregnant and lactating females.
• Smokers.

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
injectable platelet rich fibrin group	injectable platelet rich fibrin	8 patients undergo flapless single immediate implant placement surgery with filling the gap distance with i-PRF\& bone graft

Primary Outcome Measures

Name	Time	Method
Radiograhic evaluation of the effect of i-PRF on filling the buccal gap distance between the immediately placed dental implant and the surrounding bone.	6 months follow up	density, vertical and horizontal assessment of labial plate
Radiographic analysis	6 months follow up	density of labial plate

Secondary Outcome Measures

Name	Time	Method
Esthetic evaluation of the effect of i-PRF on the soft tissue around immediately placed dental implant	6 months follow up	pink esthetic score

Trial Locations

Locations (1)

Bassant Mohye; 🇪🇬 Cairo, Egypt