Comparison of haemodynamic parameters following two regimes of fractionated doses of Levobupivacaine in lower segment caesarean section under spinal anaesthesia.
Phase 3
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2023/08/056548
- Lead Sponsor
- Department of Anaesthesia,School of Medical Sciences and Research and Sharda Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Patients scheduled for LSCS under spinal anaesthesia
2.ASA class II
3.Age 18-35 years
4.Height-140-170cms
5.BMI <30kg/m2
6.Uncomplicated singleton pregnancies
7.Patient having systolic blood pressure between 110-130mm of Hg
Exclusion Criteria
1.Patient having history of any systemic illness of cardiovascular system, respiratory system, endocrine, renal or hepatic disorders.
2.Fetal distress (as diagnosed by obstetrician)
3.BMI >30% kg / m2
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the number of patients requiring mephentermine to maintain systolic blood pressure ±20% of baseline value in three groups. (Two groups of fractionated doses & one group of bolus dose). <br/ ><br> <br/ ><br>Timepoint: Perioperatively till 2 hours in same setting <br/ ><br> <br/ ><br>
- Secondary Outcome Measures
Name Time Method To compare total requirement of mephentermine among three groups <br/ ><br>To compare haemodynamic parameters HR SBP DBP MAP <br/ ><br>To compare time of onset & regression of sensory & motor block in three <br/ ><br> groups <br/ ><br>To compare neonatal outcome by APGAR score at 1 min 5 min & 10 min <br/ ><br>Timepoint: Till 2 hours post operative period