Different Effect of Isoflurane and Propofol on pre-existing valvular insufficiency in Cardiac surgery

Not Applicable

Completed

• Conditions: Diseases of the circulatory system

• Registration Number: KCT0002767
• Lead Sponsor: Samsung Medical Center

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 11 March 2019

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 54

Inclusion Criteria

1) Patients diagnosed with Mild or more valve regurgitation
2) Patients undergoing cardiac surgery under general anesthesia
3) Patients with TTE (transthoracic ultrasound) or TEE (transesophageal ultrasound) results that met the criteria of 1) and 2) and preoperative examination.
3) ASA(American society of anesthesiologists) class 1-4 patient
4) Adults who can write a consent form (ages 19 and over)

Exclusion Criteria

1) patients with paravalvular leakage in patients with previous valvular surgery.
2) Patients with overall regional wall motion abnormality (Akinesia and above).
3) Hemodynamically unstable patient.
4) Patients diagnosed with Eigenmenger syndrome
5) Patients with esophageal and gastric-related disease (formerly esophagectomy or esophagogastrectomy patients)
6) Patients with blood clotting abnormalities.
7) Patients with dysphagia
8) Women who are pregnant

Study & Design

• Study Type: Observational Study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Decreased severity of valve regurgitation compared to preoperative examination in all-vein anesthesia using propofol and inhalation anesthesia using Isoflurane

Secondary Outcome Measures

Name	Time	Method
Affecting the reduction of the severity factor (Patient characteristics, Hemodynamic change, ventilation, use of inotopics)