A study on comparison between esmolol bolus and infusion in blunting the increase in heart rate and blood pressure following intubatio

Not Applicable

Completed

• Conditions: Health Condition 1: null- ASA 1 AND 2 patients posted for elective sugery in the age group 18-70

• Registration Number: CTRI/2017/03/007994
• Lead Sponsor: Christian Medical College Vellore

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 24 November 2021

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 126

Inclusion Criteria

1. ASA 1 and ASA 2 patients

2. Patients posted only for elective non cardiac surgery

3. patients accepting to give informed written consent

Exclusion Criteria

1.Pregnancy

2.Heart rate less than 60 per minute

3.Systolic blood pressure less than 100mm Hg

4.Hepatic failure

5.Renal failure

6.Cardiac conduction abnormalities

7.Patients on beta blockers

8.History of asthma or chronic obstructive pulmonary disease

9.History of intolerance to beta blockers

10.Obesity (body mass index more than 30)

11.Total duration of laryngoscopy more than 30 seconds

12.Patients who are unable to understand and give consent for participation.

13.Patients less than 18 and more than 70 years old.

14.Patients who are part of other studies.

15.Difficult airway.

16.ASA PS III and IV.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1. Blood pressure <br/ ><br>2. Heart rateTimepoint: 1. Baseline <br/ ><br>2. preintubation 1st minute <br/ ><br>3. Preintubation 2nd minute <br/ ><br>4. postintubation - every minute for 5 minutes <br/ ><br>

Secondary Outcome Measures

Name	Time	Method
side effects such as rash, vomiting, seizuresTimepoint: 1. Baseline <br/ ><br>2. preintubation 1st minute <br/ ><br>3. Preintubation 2nd minute <br/ ><br>4. postintubation - every minute for 5 minutes