The Relationship Between Osteoporosis and Sarcopenia Parameters in Postmenopausal Women Under 60: A Cross-Sectional Study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 52
- 主要终点
- 5 times chair stand test
研究概览
简要总结
This cross-sectional study will include postmenopausal women under the age of 60 who visited the Physical Medicine and Rehabilitation outpatient clinic at Beylikdüzü State Hospital between June 25 and July 25, 2025. Participants must have undergone a bone mineral density (BMD) assessment within the past six months using Dual X-ray Absorptiometry (DXA). Both osteoporotic and non-osteoporotic patients will be enrolled. Sociodemographic data such as age, height, weight, and BMI will be recorded. Femoral neck and L1-L4 T-scores and BMD values will be obtained from existing DXA results. Information on osteoporosis treatment, presence of fecal incontinence, constipation, and medication use will be collected. In the second phase, sarcopenia will be assessed according to EWGSOP2 criteria using bioelectrical impedance analysis for skeletal muscle mass, handgrip strength, and the five-time sit-to-stand test. Differences between the osteoporotic and non-osteoporotic groups will be analyzed.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 50 Years 至 59 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Women under 60 years of age who are postmenopausal.
- •Patients with or without a diagnosis of osteoporosis:
- •Osteoporosis group: T-score ≤ -2.5 in femoral neck or L1-L4 region. Control group: T-score ≥ -1.0 in femoral neck and L1-L4 region.
- •Patients who provide written informed consent to participate in the study.
排除标准
- •Refusal to participate in the study.
- •Presence of neuromuscular diseases that could cause muscle loss.
- •History of infection, recent surgery, or trauma.
- •Presence of psychiatric disorders.
- •Cognitive impairment that could interfere with test performance or data reliability.
- •Use of medications that could affect study outcomes (e.g., corticosteroids, muscle relaxants, or medications influencing bone/muscle metabolism).
结局指标
主要结局
5 times chair stand test
时间窗: 0 day
The Five Times Sit-to-Stand Test is a simple and widely used functional assessment tool to evaluate lower extremity muscle strength, balance, and mobility.
Handgrip Strength
时间窗: 0 day
This is a simple test to measure muscle strength. Reduced handgrip strength is a sign of sarcopenia.
Skeletal Muscle Mass
时间窗: 0 day
Measured by bioelectrical impedance analysis (BIA), this assesses the amount of muscle tissue in the body. Low skeletal muscle mass indicates sarcopenia.
次要结局
未报告次要终点
研究者
Busra Sirin
Principle Investigator
Beylikduzu State Hospital