A clinical study on the effect of glycopyrrolate on the maternal blood pressure and vasopressor requirement during cesarean delivery
Not Applicable
Completed
- Conditions
- Health Condition 1: O82- Encounter for cesarean delivery without indication
- Registration Number
- CTRI/2020/12/029495
- Lead Sponsor
- JSS Medical College and Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion Criteria
Height- 150-170cm
Body mass index < 28kg/m2
Singleton pregnancy
Exclusion Criteria
Patients having contraindications to spinal anaesthesia i.e, patient refusal, local infection, allergy to local anaesthetics, bleeding disorders, spinal deformity, severe congenital or acquired heart disease, hemorrhage or hypovolemic shock (each condition ruled out via good history, clinical examination, & or investigations)
Known sensitivity to the study drugs
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The incidence of hypotension and vasopressor requirement during spinal anaesthesia for cesarean deliveryTimepoint: Hypotension is assessed from 1 minute after administration of spinal anaesthesia up to 60 minutes or end of surgery whichever is the earliest. <br/ ><br>Total amount IV Ephedrine 6mg given intra-operative period from 1 minute of spinal-anaesthesia administration up to the end of surgery.
- Secondary Outcome Measures
Name Time Method Incidence of bradycardia and requirement of atropine <br/ ><br>Incidence of nausea, vomiting and dryness of mouth. <br/ ><br>Time for onset , maximum level and duration of sensory block <br/ ><br>Time for 2 segment regression of sensory block <br/ ><br>Time for onset of motor block, maximum level and duration of motor block <br/ ><br>APGAR score <br/ ><br>Timepoint: Bradycardia below 60 beats/min. Effect of spinal anesthesia on motor and sensory blockade.