Cardiac sympathetic activity in 22q11 deletion syndrome.

Recruiting

• Conditions: cardiale sympathische activiteit; cardiac nerve activity; cardiac sympathetic innervation; 10007521; 10014699

• Registration Number: NL-OMON35870
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 20

Inclusion Criteria

patients with the 22q11 deletion syndrome, confirmed by genetic analysis

Exclusion Criteria

- Congenital hart disease
- Use of medication that might influence dopamine and norepinephrine concentrations
- Pregnancy
- Known allergy to iodine

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Difference in cardiac sympathetic activity as assessed with 123I-MIBG between<br /><br>subject with 22q11DS and healthy subjects, with and without cathecholamine<br /><br>depletion.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>not applicable</p><br>