Loaded Breathing Training in Essential Hypertension

Not Applicable

Terminated

• Conditions: Essential Hypertension
• Interventions: Device: ULB , LB

• Registration Number: NCT00791986
• Lead Sponsor: Khon Kaen University

Brief Summary

The purpose of this study is to determine whether adding load to slow controlled breathing training could enhance blood pressure lowering in patients with essential hypertension.

Detailed Description

Hypertension (HT) is one of the major risk of cardiovascular diseases and cost of pharmacological treatment is a very high. Lifestyle modification is the first trial in stage 1 hypertension before commencing pharmacological treatment and a co-treatment with drug in hypertensive patient. Slow paced breathing training and physical training has been shown to reduce both systolic and diastolic blood pressure in HT. Moreover loaded breathing was reported to be able to decrease blood pressure in healthy. Loaded slow breathing training may enhance the antihypertensive effect of slow paced breathing.

Study Timeline

• Study Start: 2006-05
• Primary Completion: 2007-12
• Study First Submitted: 2008-11-14
• Study First Submitted QC: 2008-11-14
• Study First Posted: 2008-11-17
• Study Completion: 2008-12
• Status Verified: 2018-03
• Last Update Submitted: 2018-03-05
• Last Update Posted: 2018-03-07

Recruitment & Eligibility

• Status: TERMINATED
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• Clinical diagnosis of essential hypertension stage I-II

Exclusion Criteria

• Respiratory disease
• Diabetes mellitus
• Heart disease
• Renal disease
• Cerebrovascular disease
• Dyslipidemia
• Pregnancy

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: FACTORIAL

Arm && Interventions

Group	Intervention	Description
ULB	ULB , LB	The patients conduct controlled slow breathing training using the WPTB device without inspiratory resistance.
LB	ULB , LB	The patients breath in against resistance using WPTB device.

Primary Outcome Measures

Name	Time	Method
Home blood pressure	Pre- and post - 8 weeks of intervention at rest

Secondary Outcome Measures

Name	Time	Method
Office blood pressure	Pre- and post- 8 weeks of intervention at rest
Exercising blood pressure	Blood pressure during exercise at pre- and post-8 weeks of intervention
Heart rate variability	Heart rate variability at pre-and post- 8 weeks of intervention

Trial Locations

Locations (1)

Cardiopulmonary Physical Therapy Research Room, Faculty of Asociated Medical Sciences, Khon Kaen University.; 🇹🇭 Khon Kaen, Thailand