Effect of Prebiotic in Clinical and Paraclinical Parameters of Poly Cystic Ovarian Syndrom (PCOS)
- Conditions
- clinical parameters.Polycystic ovarian syndrome
- Registration Number
- IRCT2016062810324N33
- Lead Sponsor
- Vice chancellor for research, Tabriz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 62
Confirming the diagnosis of PCOS by research collaborator; Age between 18 and 45 years old; Having literacy of reading and writing for completing the questionnaires; BMI between 25 and 40 kg/m2; Not taking of probiotic, prebiotics, vitamins, minerals and omega-3 during the study and three months before the intervention
Exclusion criteria: Having other androgenic disorders such as adrenal hyperplasia or Androgen-secreting tumor according to assessment of research collaborator; Having thyroid diseases according to assessment of research collaborator; Having Cushing's syndrome according to assessment of research collaborator; Using of hormonal contraceptive drugs at present or previous use of hormone therapy; Pregnancy or breast-feeding; Having previous surgery on one or both ovaries; Using of cigarettes and alcohol; Severe physical activity (this is activity that during carrying out it, an individual can’t easily talk due to increased respiratory rate and breathing); Using of Dietary supplements
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Hirsutism Score. Timepoint: Before study, three and six months after starting the intervention. Method of measurement: Ferriman–Gallwey criteria.;Serum Levels of hormonal indices (DHEA-S, free testostrone). Timepoint: Before study and three months after starting the intervention. Method of measurement: Blood tests.
- Secondary Outcome Measures
Name Time Method Anthropometric indices (Waist circumference, hip circumference and body mass index). Timepoint: before intervention, three and six months after starting the intervention. Method of measurement: Measuring with centimeter and scale.;Serum levels of FBS, hsCRP and Lipid profile. Timepoint: before intervention and three months after starting the intervention. Method of measurement: Blood tests.;Side events. Timepoint: During the study. Method of measurement: Checklist.