In-exsufflation mechanics in intubated patients

Not Applicable

Completed

• Conditions: Acute Respiratory Failure requiring mechanical ventilation and endotracheal tube intubation; Respiratory; Acute respiratory failure

• Registration Number: ISRCTN25106564
• Lead Sponsor: Philips Respironics (France)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2013-11-26
• Study Completion: 2016-12-31
• Last Update Posted: 12 February 2018

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 67

Inclusion Criteria

1. Patient ventilated on endotracheal tube for less than 7 days
2. Duration of mechanical ventilation predicted > 48h; 1. Patient ventilated on endotracheal tube for less than 7 days
2. Duration of mechanical ventilation predicted > 48h

Exclusion Criteria

1. Pre-existing neuromuscular pathology, suspected or proven
2. State of shock uncontrolled defined by the administration of norepinephrine or adrenaline at a dose> 0.3 mcg/kg/min
3. Moderate to severe acute respiratory distress syndrome (ARDS) defined by a PaO2/FiO2 ratio <200 mmHg
4. Undrained pneumothorax
5. Hemoptysis active or less than 15 days
6. Intracranial hypertension
7. Decision to limit or stop the treatment
8. Pregnancy
9. Unable to follow study related procedures as explained by the investigator
10. Minor patient; 1. Pre-existing neuromuscular pathology, suspected or proven
2. State of shock uncontrolled defined by the administration of norepinephrine or adrenaline at a dose> 0.3 mcg/kg/min
3. Moderate to severe acute respiratory distress syndrome (ARDS) defined by a PaO2/FiO2 ratio <200 mmHg
4. Undrained pneumothorax
5. Hemoptysis active or less than 15 days
6. Intracranial hypertension
7. Decision to limit or stop the treatment
8. Pregnancy
9. Unable to follow study related procedures as explained by the investigator
10. Minor patient

Study & Design

• Study Type: Interventional
• Study Design: Not specified