nraveling genetic causes of congenital multiple pituitary hormone deficiencies

Completed

• Conditions: Congenital multiple pituitary hormone deficiency (MPHD); congenital hypopituitarism; 10014699; 10021112

• Registration Number: NL-OMON38016
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 60

Inclusion Criteria

Patients with congenital MPHD, a pituitary MRI image consisting of an ectopic posterior pituitary gland and an absent or thin pituitary stalk. Parents of abovementioned patients.
Parents must be able to read and understand the written information.

Exclusion Criteria

None

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Detection of genes causing congenital MPHD in patients with an ectopic<br /><br>posterior pituitary gland and absent or thin pituitary stalk.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Understanding of the molecular and cellular mechanisms leading to congenital<br /><br>MPHD in patients with an ectopic posterior pituitary gland and absent or thin<br /><br>pituitary stalk.<br /><br>Increase our understanding of pituitary development in man.</p><br>