Comparison of Levobupivacaine (0.5%) and Ropivacaine (0.75%) in Lower Limb Surgeries under Spinal Anaesthesia

Not Applicable

• Conditions: Health Condition 1: X58- Exposure to other specified factors

• Registration Number: CTRI/2024/05/066935
• Lead Sponsor: RM Medical College

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 27 May 2024

Recruitment & Eligibility

• Status: ot Yet Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

ASA GRADE I and II

Age between 18 to 65 years

Patients undergoing lower limb Surgeries

Exclusion Criteria

Patient Refusal

Infection at the Injection Site

Coagulopathy

Increased Intracranial Pressure

Known Allergy or Hypersensitivity to Local Anaesthetic Agents

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The primary outcome is to study the efficacy of the drug based on Duration of motor blockade , assessed by Modified Bromage scale.Timepoint: Baseline vitals will be noted. After Spinal anesthesia, Haemodynamic parameters ( SBP,DBP,MAP,HR), Loss of sensory and motor function will be noted every 1 minute for first 5 minutes, every 2 minutes for next 10 minutes, every 5 minutes for next 25 minutes and then every 30 minutes till regression of block.

Secondary Outcome Measures

Name	Time	Method
1.To compare and Evaluate Onset of sensory block in both the groups <br/ ><br>2.To compare and Evaluate Onset of motor block in both the groups <br/ ><br>3.To compare and Evaluate Duration of Motor block in both the groups <br/ ><br>4.To compare and Evaluate time of first rescue Analgesia in both the groups <br/ ><br>5.To compare hemodynamic changes if any <br/ ><br>6.Complications if any in both the groupsTimepoint: Baseline vitals will be noted. After Spinal anesthesia, Haemodynamic parameters ( SBP,DBP,MAP,HR), Loss of sensory and motor function will be noted every 1 minute for first 5 minutes, every 2 minutes for next 10 minutes, every 5 minutes for next 25 minutes and then every 30 minutes till regression of block.