The association of genetic variants and outcome of in vitro fertilization cycles
Not Applicable
Completed
- Conditions
- In vitro fertilization (IVF)Pregnancy and Childbirth
- Registration Number
- ISRCTN12768989
- Lead Sponsor
- Chung Shan Medical Unviersity Hospital
- Brief Summary
2019 Results article in https://pubmed.ncbi.nlm.nih.gov/30857124/ (added 15/02/2023) 2021 Results article in https://pubmed.ncbi.nlm.nih.gov/34209056/ (added 15/02/2023)
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Female
- Target Recruitment
- 2000
Inclusion Criteria
1. Age 20 to 45 years old
2. Infertile patients who need IVF treatment
3. Qualified for IVF treatment
Exclusion Criteria
1. Part of the oocyte donation program
2. Part of the sperm donation program
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Oocyte number, measured using microscopy observation at the time of oocyte retrieval
- Secondary Outcome Measures
Name Time Method <br> 1. Embryo quality is measured using microscopy observation for the number of blastomere, fragmentation degree at day 3 or day 5 after oocyte retrieval<br> 2. Pregnancy rate is measured using serum beta-HCG test and ultrasound examination at 18 days and 32 days after oocyte retrieval, respectively<br> 3. Implantation rate is measured using the total sac numbers divided by total transfer embryo number at the time of ultrasound examination<br>