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Study on the antidepressant neural circuitry of Chaihu Shugansan based on BOLD-fMRI

Phase 4
Recruiting
Conditions
Premature ejaculation with depression
Registration Number
ITMCTR2100004835
Lead Sponsor
Jiangsu Privince Hospital of Chinese Medicine
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
Male
Target Recruitment
Not specified
Inclusion Criteria

1.In line with the diagnosis of western medicine and Chinese medicine syndrome differentiation standards;
2.Aged 18 to 45 years;
3.Junior high school education or above;
4.The han nationality;
5.Right-handed;
6.Stable sexual partner for more than 6 months;
7.IIEF-5 score > 21;
8.HAMD score 8-17.

Exclusion Criteria

1.Combined with other sexual dysfunction;
2.The spouse has sexual dysfunction;
3.Systemic disease with severe physical diseases, such as cardiovascular, liver, kidney, endocrine, hematopoietic, nervous system diseases, and a history of drug/alcohol or substance abuse within the past 6 months, as well as a history of long-term antipsychotic medication or mental disorders;
4.Into the group before half a month had affect ejaculation function of drugs;
5.Currently participating in, or has withdrawn within the past 30 days from, another clinical study that is not compatible with this study;
6.MRI examination contraindicated;
7.Suicidal tendencies;
8.There are fertility requirements in the next three months.

Study & Design

Study Type
Interventional study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Hamilton Depression scale;Oxygen levels are dependent on brain Functional imaging;
Secondary Outcome Measures
NameTimeMethod
Diagnostic scale for premature ejaculation;
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