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Modulating connectivity with non-invasive brain stimulation during spatial neglect rehabilitatio

Recruiting
Conditions
obstruction of a blood vessel or bleeding in the brain
stroke
10007963
Registration Number
NL-OMON52644
Lead Sponsor
niversiteit Maastricht
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
Not specified
Target Recruitment
40
Inclusion Criteria

- 30-80 years of age
- Subacute stroke (stroke occurred more than 2 weeks and less than 6 months
ago; first or recurrent, ischemic or intracerebral haemorrhagic lesion)
- Diagnosed visuospatial neglect and/or spatial neglect symptoms (either left
or right sided) on the basis of clinical judgement (i.e. by the cooperating
clinical (neuro)psychologist based on intake and neuropsychological assessment).
- Sufficient comprehension and communication skills to benefit from training,
on the basis of clinical judgement
(i.e. by the cooperating clinical (neuro)psychologist based on intake and
neuropsychological assessment).

Exclusion Criteria

- Physically or mentally unable to participate (e.g. to perform the neglect
training)
- Severe communicative disability, including aphasia
- Local scalp injuries
- Eczema on scalp or psoriasis
- (Neuro)psychiatric or neurodegenerative diseases including epilepsy (in case
patient had one or more seizures in the last 2 years and/or had anti-epileptic
medication in the last 2 years), dementia, serious depression, multiple
sclerosis, Parkinson*s disease, Huntington*s disease on the basis of clinical
judgement (i.e. cooperating (neuro)psychologist)
- Current alcohol and/or drug abuse or a history of abuse within the last 6
months
- Pregnancy

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
<p>To investigate whether the application of dual-site transcranial alternating<br /><br>current stimulation during cognitive training improves spatial neglect symptoms<br /><br>to a larger extent than the application of sham stimulation during cognitive<br /><br>training. </p><br>
Secondary Outcome Measures
NameTimeMethod
<p>To investigate whether the application of dual-site transcranial alternating<br /><br>current stimulation during cognitive training ameliorates neglect behaviour in<br /><br>activities of daily living (ADL) to a larger extent than the application of<br /><br>sham stimulation during cognitive training. </p><br>
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