Comparative evaluation of efficacy of Vitamin D3 supplements using biomarkers on orthodontic tooth movement in patients with Vitamin D insufficiency
Not Applicable
- Registration Number
- CTRI/2020/04/024563
- Lead Sponsor
- Dr Megha Jain
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
No gross skeletal dysplasia, that can be treated by orthodontic treatment alone with the extraction of two or more premolars
Subjects serum 25-hydroxyvitamin D levels between 21-29ng/ml
Subjects providing consent for participation in the study
Exclusion Criteria
Subjects with hematological/medical condition that limits or restricts the hematological investigation will be eliminated
Any medical condition or medication that is known to affect the bone metabolism (such as metabolic disorder, chronic inflammatory disease, hormonal replacement therapy, menopause, liver disease, renal disease, pregnancy, lactation,)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method serum levels of 25-hydroxyvitamin D between 30ng/ml -100ng/ml And <br/ ><br>improvement in boneturnover markers in gingival Crevicular fluidTimepoint: 3-4 weeks for serum levels of 25-hydroxyvitamin D <br/ ><br>one week for Bone Turnover Markers
- Secondary Outcome Measures
Name Time Method noneTimepoint: 0