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临床试验/NCT01792011
NCT01792011已完成4 期

Accuracy and Utility of the Pleth Variability Index as a Predictor of Fluid Responsiveness During the Dissection and Anhepatic Phase of Liver Transplantation

Inonu University2 个研究点 分布在 1 个国家目标入组 25 人开始时间: 2012年10月最近更新:
适应症

试验速览

阶段
4 期
状态
已完成
入组人数
25
试验地点
2
主要终点
To test the ability of PVI to detect changes in preload during orthotopic liver transplantation

研究概览

简要总结

The aim of this study is to compare the accuracy of PVI (pleth variability index)

详细描述

The aim of this study is to compare the accuracy of PVI (pleth variability index)with other hemodynamic variability that measured with PİCCO (SVV, PPV, CVP,CI)to predict the response of cardiac index to volume replacement in patients undergoing liver transplantation.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Diagnostic
盲法
Single (Outcomes Assessor)

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Elective living donor liver transplantation,
  • >18 years patients

排除标准

  • Patients with:
  • Arrhythmia
  • Reduced left ventricular function (EF<40%)
  • Hepatocellular carcinoma
  • Pulmonary hypertension
  • Fulminant liver failure
  • valvular heart disease

结局指标

主要结局

To test the ability of PVI to detect changes in preload during orthotopic liver transplantation

时间窗: During dissection and anhepatic phase (3 months)

PVI is a measure of the dynamic changes in perfusion index that occur during a complete respiratory cycle

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Gulay ERDOGAN KAYHAN

MD,Asistant Professor Dr

Inonu University

研究点 (2)

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