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Evaluation of Potential Vitamin D Effects on Muscle: a Pilot Study

Not Applicable
Completed
Conditions
Fecal Incontinence
Dysphagia
Urinary Incontinence
Interventions
Other: Ergocalciferol (vitamin D2)
Registration Number
NCT00593996
Lead Sponsor
University of Wisconsin, Madison
Brief Summary

People who do not have adequate amounts of vitamin D develop weakness of leg and arm muscles. This study will determine if vitamin D supplementation benefits muscle functions important for swallowing, bladder and bowel function.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
50
Inclusion Criteria
  • Patients who present for evaluation to the UW Geriatric clinic including Dr. Pryzbelski's subspecialty, or Osteoporosis clinics
  • Age 70 years or older
  • Cognitively intact, as determined by the attending physicians at above mentioned clinics
Exclusion Criteria
  • History of, on ongoing, renal failure
  • History of liver failure
  • Known malabsorption
  • Known disorders of parathyroid function, hyper/hypocalcemia, or other abnormalities of calcium or phosphate metabolism
  • Known history of vitamin D intoxication or granulomatous disease
  • active seizure disorder
  • Pain associated with temporomandibular joint (TMJ)

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
1Ergocalciferol (vitamin D2)oral placebo 3 times weekly
Primary Outcome Measures
NameTimeMethod
change in lingual strength and perceived swallow function4 weeks
Secondary Outcome Measures
NameTimeMethod
change in perceived bowel and bladder function4 weeks

Trial Locations

Locations (1)

UW Osteoporosis Clinical Research Program

🇺🇸

Madison, Wisconsin, United States

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