Relation Between Neutrophil to Lymphocyte Ratio and Peripheral Artery Disease in Regular Hemodialysis Patients at Sohag University Hospital
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 120
- 试验地点
- 1
- 主要终点
- The aim of this study is to evaluate the predictive value of the neutrophil-to- lymphocyte ratio (NLR) for the presence of peripheral artery disease (PAD) in patients undergoing regular hemodialysis.
研究概览
简要总结
Recent studies have reinforced the association between high NLR and PAD in hemodialysis patients. This highlights the need for further studies to confirm its predictive value and determine optimal cut-off thresholds tailored to local patient populations. Accordingly, the present study aims to investigate the relationship between NLR and the presence of PAD in patients undergoing regular hemodialysis. By establishing this association in a well-defined population, we hope to provide evidence that supports the use of NLR as a simple, cost-effective tool for PAD risk stratification and early intervention
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adult patients aged ≥18 years.
- •Undergoing maintenance hemodialysis for at least 3 months (thrice weekly)
- •Able to provide informed consent.
- •Willing to undergo clinical and laboratory evaluations, including peripheral vascular assesment
排除标准
- •Active infection or sepsis at the time of evaluation
- •.* Patients who have a sedimentation rate of more than 60 mm/hour
- •*. Known autoimmune or hematologic disorders that may influence leukocyte count.
- •Current use of immunosuppressive therapy, corticosteroids, or chemotherapy.
- •History of malignancy.
- •Patients with incomplete medical records or unable to undergo peripheral vascular assessment.
结局指标
主要结局
The aim of this study is to evaluate the predictive value of the neutrophil-to- lymphocyte ratio (NLR) for the presence of peripheral artery disease (PAD) in patients undergoing regular hemodialysis.
时间窗: 6months
% of patients with affection in neutrophills to lymphocytes ratio in parient on regular hemodialysis.
时间窗: 6 months
次要结局
未报告次要终点
研究者
Islam Gamal Salem
Resident physician in the Department of General Internal Medicine
Sohag University