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Cysteine

Generic Name
Cysteine
Brand Names
Elcys, Freamine 6.9, Freamine III 10, Hepatamine 8, Nephramine, Nouress, Premasol, Primene, Procalamine 3, Trophamine 10 %
Drug Type
Small Molecule
Chemical Formula
C3H7NO2S
CAS Number
52-90-4
Unique Ingredient Identifier
K848JZ4886
Background

A thiol-containing non-essential amino acid that is oxidized to form cystine.

Indication

For the prevention of liver damage and kidney damage associated with overdoses of acetaminophen

Associated Therapies
Total parenteral nutrition therapy, Amino acid supplementation

The FIGHT-RP1 Study

Phase 1
Completed
Conditions
Retinitis Pigmentosa
Interventions
First Posted Date
2017-02-24
Last Posted Date
2022-09-19
Lead Sponsor
Johns Hopkins University
Target Recruit Count
30
Registration Number
NCT03063021
Locations
🇺🇸

Wilmer Eye Institute, Johns Hopkins, Baltimore, Maryland, United States

Antioxidant Use in Diabetes to Reduce Oxidative Stress

Early Phase 1
Terminated
Conditions
Ameliorating Oxidative Stress in Type 1 Diabetes
Interventions
Dietary Supplement: Placebo
Dietary Supplement: omega 6 Fish oil ( PUFA)
First Posted Date
2017-02-16
Last Posted Date
2022-03-22
Lead Sponsor
University of Maryland, Baltimore
Target Recruit Count
8
Registration Number
NCT03056014
Locations
🇺🇸

University of Maryland, Baltimore, Baltimore, Maryland, United States

N-Acetylcysteine for Youth Cannabis Use Disorder

Phase 2
Completed
Conditions
Cannabis Use Disorder
Interventions
Drug: Placebo oral capsule
First Posted Date
2017-02-16
Last Posted Date
2024-12-17
Lead Sponsor
Medical University of South Carolina
Target Recruit Count
192
Registration Number
NCT03055377
Locations
🇺🇸

Medical University of South Carolina, Charleston, South Carolina, United States

N-acetylcysteine in the Treatment of Depressive Symptoms in Bipolar Offspring

Not Applicable
Conditions
Depression
Interventions
First Posted Date
2016-08-12
Last Posted Date
2018-05-14
Lead Sponsor
University of Cincinnati
Target Recruit Count
22
Registration Number
NCT02865629
Locations
🇺🇸

University of Cincinnati, Department of Psychiatry & Behavioral Neuroscience, Cincinnati, Ohio, United States

A Study of Oxidative Pathways in MS Fatigue

Phase 2
Completed
Conditions
Fatigue
Progressive Multiple Sclerosis
Interventions
First Posted Date
2016-06-17
Last Posted Date
2024-07-09
Lead Sponsor
University of California, San Francisco
Target Recruit Count
15
Registration Number
NCT02804594
Locations
🇺🇸

University of California San Francisco, San Francisco, California, United States

Glutathione Levels and Compulsivity

Not Applicable
Completed
Conditions
Compulsive Behavior
Anorexia Nervosa
Interventions
First Posted Date
2016-06-09
Last Posted Date
2018-11-07
Lead Sponsor
University of Oxford
Target Recruit Count
23
Registration Number
NCT02794389
Locations
🇬🇧

Department of Psychiatry, University of Oxford, Oxford, Oxfordshire, United Kingdom

NAC Trial for Anosmia

Early Phase 1
Completed
Conditions
Anosmia
Interventions
First Posted Date
2015-06-25
Last Posted Date
2018-03-20
Lead Sponsor
University of Miami
Target Recruit Count
29
Registration Number
NCT02481609
Locations
🇺🇸

University of Miami, Miller School of Medicine, Clinical Research Building, Miami, Florida, United States

N-acetyl Cysteine for Ovulation Induction in Clomiphene Citrate Resistant Polycystic Ovary Syndrome

Phase 4
Completed
Conditions
Polycystic Ovary Syndrome
Interventions
Procedure: laparoscopic ovarian drilling
First Posted Date
2014-09-12
Last Posted Date
2014-09-12
Lead Sponsor
Assiut University
Target Recruit Count
70
Registration Number
NCT02239107

A Randomized Double Blinded Study to Examine the Use of N-acetyl Cysteine for the Prevention and Treatment of HAAF in Patients With Type 1 Diabetes

Phase 1
Completed
Conditions
Hypoglycemia Unawareness
Type 1 Diabetes
Interventions
First Posted Date
2014-08-01
Last Posted Date
2020-01-31
Lead Sponsor
University of Minnesota
Target Recruit Count
22
Registration Number
NCT02206152
Locations
🇺🇸

University of Minnesota Department of Medicine, Division of Diabetes, Endocrinology and Metabolism, Minneapolis, Minnesota, United States

Glutamate-Glutamine Cycling (VCYC) During Cocaine Abstinence Using 1H-MRS

Phase 1
Completed
Conditions
Healthy
Cocaine Dependence
Interventions
Diagnostic Test: 1H MRS
Diagnostic Test: [11C]APP311 PET scan
Diagnostic Test: [18F]FDG PET scan
First Posted Date
2014-04-28
Last Posted Date
2023-07-07
Lead Sponsor
Yale University
Target Recruit Count
6
Registration Number
NCT02124941
Locations
🇺🇸

Connecticut Mental Health Center, New Haven, Connecticut, United States

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