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Cysteine

Generic Name
Cysteine
Brand Names
Elcys, Freamine 6.9, Freamine III 10, Hepatamine 8, Nephramine, Nouress, Premasol, Primene, Procalamine 3, Trophamine 10 %
Drug Type
Small Molecule
Chemical Formula
C3H7NO2S
CAS Number
52-90-4
Unique Ingredient Identifier
K848JZ4886
Background

A thiol-containing non-essential amino acid that is oxidized to form cystine.

Indication

For the prevention of liver damage and kidney damage associated with overdoses of acetaminophen

Associated Therapies
Total parenteral nutrition therapy, Amino acid supplementation

N-Acetylcysteine Protection Against Radiation Induced Cellular Damage

Phase 2
Recruiting
Conditions
Cardiac Arrhythmia
Interventions
First Posted Date
2019-11-07
Last Posted Date
2023-08-02
Lead Sponsor
Centro Cardiologico Monzino
Target Recruit Count
550
Registration Number
NCT04154982
Locations
🇮🇹

Centro Cardiologico Monzino, Milano, MI, Italy

N-acetyl Cysteine in Post-reperfusion Pulmonary Injury in Chronic Thromboembolic Pulmonary Hypertension.

Not Applicable
Conditions
Chronic Thromboembolic Pulmonary Hypertension
Interventions
First Posted Date
2019-09-06
Last Posted Date
2020-09-22
Lead Sponsor
Instituto Nacional de Cardiologia Ignacio Chavez
Target Recruit Count
34
Registration Number
NCT04081012
Locations
🇲🇽

Instituto Nacional Ignacio Chavez, Ciudad de mexico, Mexico

Signatures of N-Ac for Non-Suicidal Self-Injury in Adolescents

Phase 2
Completed
Conditions
Self-Harm
Depression
Suicide
Interventions
Drug: Placebo oral tablet
First Posted Date
2019-07-02
Last Posted Date
2023-08-15
Lead Sponsor
University of Minnesota
Target Recruit Count
44
Registration Number
NCT04005053
Locations
🇺🇸

University of Minnesota, Minneapolis, Minnesota, United States

Intravenous N-acetylcysteine and Oseltamivir Versus Oseltamivir in Adults Hospitalized With Influenza and Pneumonia

Phase 3
Recruiting
Conditions
Influenza
Interventions
Drug: 5% Dextrose
First Posted Date
2019-04-03
Last Posted Date
2023-11-27
Lead Sponsor
Chinese University of Hong Kong
Target Recruit Count
160
Registration Number
NCT03900988
Locations
🇭🇰

Prince of Wales Hospital, Hong Kong, Hong Kong

Supportive Measures in Treatment of Aluminum Phosphide Poisoning

Phase 4
Completed
Conditions
Detection of Different Prognostic Factors and Their Relation With the Outcome
Using New Protocol to Prove the Role of N-acetyl Cysteine and Adequate Supportive Measures in Aluminum Phosphide Poisoning
Interventions
First Posted Date
2019-03-18
Last Posted Date
2019-03-18
Lead Sponsor
Assiut University
Target Recruit Count
44
Registration Number
NCT03879356

NAC Effect on Hox Genes Expressions in RIF

Phase 3
Completed
Conditions
Female Infertility
Interventions
First Posted Date
2019-03-05
Last Posted Date
2019-03-05
Lead Sponsor
Royan Institute
Target Recruit Count
40
Registration Number
NCT03862586

N-Acetyl Cysteine in the Prevention of Contrast Induced Nephropathy in Cirrhosis of Liver-NEPHRO Trial

Not Applicable
Completed
Conditions
Liver Cirrhoses
Interventions
Drug: Placebo Oral Tablet
First Posted Date
2018-11-29
Last Posted Date
2019-11-04
Lead Sponsor
Institute of Liver and Biliary Sciences, India
Target Recruit Count
100
Registration Number
NCT03759158
Locations
🇮🇳

Institute of Liver and Biliary Sciences, New Delhi, Delhi, India

Vitamin E and N-acetylcysteine for Preventing Contrast-Induced Acute Kidney Injury After Coronary Artery Catheterization

Phase 3
Conditions
Contrast-induced Nephropathy
Coronary Artery Angiography
Stable Angina
Coronary Catheterization
Coronary Artery Disease
Acute Coronary Syndrome
Interventions
Drug: Placebo oral capsule
Drug: Placebos
Drug: Normal Saline Flush, 0.9% Injectable Solution
First Posted Date
2018-11-28
Last Posted Date
2018-11-30
Lead Sponsor
Rajaie Cardiovascular Medical and Research Center
Target Recruit Count
1000
Registration Number
NCT03755700
Locations
🇮🇷

Rajaie cardiovascular medical and research center, Tehran, Iran, Islamic Republic of

Brain Imaging to Understand the Role of Inflammation in N-Acetyl Cysteine (NAC) Treatment of Bipolar Depression

Early Phase 1
Completed
Conditions
Bipolar Disorder
Depression
Interventions
First Posted Date
2018-11-05
Last Posted Date
2021-08-05
Lead Sponsor
Martin Lan
Target Recruit Count
3
Registration Number
NCT03730064
Locations
🇺🇸

Columbia University Medical Center, New York, New York, United States

Adjunctive NAC in Adult Patients With Pulmonary Tuberculosis

Phase 2
Completed
Conditions
Tuberculosis, Pulmonary
Interventions
First Posted Date
2018-10-11
Last Posted Date
2024-11-11
Lead Sponsor
The Aurum Institute NPC
Target Recruit Count
110
Registration Number
NCT03702738
Locations
🇹🇿

NIMR-Mbeya Medical Research Centre, Mbeya, Tanzania

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