MedPath

Cysteine

Generic Name
Cysteine
Brand Names
Elcys, Freamine 6.9, Freamine III 10, Hepatamine 8, Nephramine, Nouress, Premasol, Primene, Procalamine 3, Trophamine 10 %
Drug Type
Small Molecule
Chemical Formula
C3H7NO2S
CAS Number
52-90-4
Unique Ingredient Identifier
K848JZ4886
Background

A thiol-containing non-essential amino acid that is oxidized to form cystine.

Indication

For the prevention of liver damage and kidney damage associated with overdoses of acetaminophen

Associated Therapies
Total parenteral nutrition therapy, Amino acid supplementation

Optimization of Blood Levels of 25(OH)-Vitamin D in African Americans

Early Phase 1
Completed
Conditions
Vitamin D Deficiency
Interventions
Drug: Placebo
Drug: Vitamin D + L-cysteine
First Posted Date
2021-06-25
Last Posted Date
2023-06-08
Lead Sponsor
Louisiana State University Health Sciences Center Shreveport
Target Recruit Count
165
Registration Number
NCT04939792
Locations
🇺🇸

Louisiana State University Health Shreveport, Shreveport, Louisiana, United States

N-ACETYLCYSTEINE FOR THROMBOLYSIS IN ACUTE STROKE

Phase 2
Conditions
Stroke, Ischemic
Interventions
First Posted Date
2021-06-09
Last Posted Date
2021-06-09
Lead Sponsor
University Hospital, Caen
Target Recruit Count
19
Registration Number
NCT04920448
Locations
🇫🇷

CHU Caen, Caen, Normandy, France

N-acetyl Cysteine: the Effectiveness and Safety in a Cohort of Pediatric Patients With Chronic Kidney Disease

Phase 2
Completed
Conditions
Chronic Kidney Diseases
Interventions
First Posted Date
2021-06-07
Last Posted Date
2023-04-11
Lead Sponsor
Beni-Suef University
Target Recruit Count
50
Registration Number
NCT04916080
Locations
🇪🇬

Beni-Suef university hospital, Banī Suwayf, Egypt

🇪🇬

Pediatric nephrology and transplantation unite.Aboelrish children hospital, Cairo, Egypt

Effect of High-Dose NAC on Patients With DPN

Phase 4
Conditions
Diabetic Neuropathies
Interventions
First Posted Date
2021-02-23
Last Posted Date
2022-08-08
Lead Sponsor
Ain Shams University
Target Recruit Count
30
Registration Number
NCT04766450
Locations
🇪🇬

Demerdash Hospital, Cairo, Egypt

N-acetyl Cysteine for the Prevention of Oral Mucositis After Autologous Hematopoietic Cell Transplantation.

Phase 3
Conditions
Mucositis
Transplant-Related Disorder
Interventions
First Posted Date
2021-02-16
Last Posted Date
2021-02-16
Lead Sponsor
moshe yeshurun
Target Recruit Count
116
Registration Number
NCT04756622

Oxidative Stress and Surgical Recovery

Phase 2
Completed
Conditions
Surgical Recovery
Pain, Postoperative
Interventions
Other: Normal Saline
First Posted Date
2021-02-01
Last Posted Date
2025-04-30
Lead Sponsor
Stanford University
Target Recruit Count
30
Registration Number
NCT04732000
Locations
🇺🇸

Stanford University School of Medicine, Stanford, California, United States

N-Acetylcysteine for Smoking Cessation in Tobacco and Cannabis Co-Use

Phase 4
Active, not recruiting
Conditions
Drug Use Disorder
Cannabis Use
Tobacco Use Disorder
Interventions
Other: Placebo comparator
Behavioral: Cognitive behavioral therapy (CBT)
First Posted Date
2020-11-13
Last Posted Date
2025-02-26
Lead Sponsor
Ellen Herbst
Target Recruit Count
59
Registration Number
NCT04627922
Locations
🇺🇸

San Francisco Veterans Affairs Medical Center, San Francisco, California, United States

Antioxidants as Adjuvant Therapy to Standard Therapy in Patients With COVID-19

Not Applicable
Completed
Conditions
Pneumonia, Viral
Covid19
ARDS
Oxidative Stress
Interventions
First Posted Date
2020-09-30
Last Posted Date
2021-05-21
Lead Sponsor
Unidad Temporal COVID-19 en Centro Citibanamex
Target Recruit Count
110
Registration Number
NCT04570254
Locations
🇲🇽

Unidad Temporal COVID-19 en Centro Citibanamex, Mexico City, Mexico

Trial of Famotidine & N-Acetyl Cysteine for Outpatients With COVID-19

Phase 1
Terminated
Conditions
Covid19
Interventions
First Posted Date
2020-09-10
Last Posted Date
2022-02-18
Lead Sponsor
Prisma Health-Upstate
Target Recruit Count
2
Registration Number
NCT04545008
Locations
🇺🇸

Prisma Health Greer Memorial Hospital, Greer, South Carolina, United States

🇺🇸

Prisma Health Baptist Easley Hospital, Easley, South Carolina, United States

🇺🇸

Prisma Health Greenville Memorial Hospital, Greenville, South Carolina, United States

Effectiveness of N-acetyl Cysteine, Acetyl L- Carnitine and Medicated Paraffin Oil in Aluminium Phosphide Poisoning

Phase 4
Conditions
the Study Focus to Improve the Standard of Care Used for Aluminuim Phosphide Poisoning and to Save Patients With the Minimal Organ Damage
Interventions
Dietary Supplement: acetyl L-carnitine
Drug: medicated paraffin oil
First Posted Date
2020-08-12
Last Posted Date
2020-08-12
Lead Sponsor
Cairo University
Target Recruit Count
100
Registration Number
NCT04509258
Locations
🇪🇬

Poison Control Center of Ain-Shams University hospitals, Cairo, Abbasya, Egypt

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