Vancomycin

Generic Name
Vancomycin
Brand Names
Firvanq, Vancocin
Drug Type
Small Molecule
Chemical Formula
C66H75Cl2N9O24
CAS Number
1404-90-6
Unique Ingredient Identifier
6Q205EH1VU
Background

Antibacterial obtained from Streptomyces orientalis. It is a glycopeptide related to ristocetin that inhibits bacterial cell wall assembly and is toxic to kidneys and the inner ear.
...

Indication

Administered intravenously, vancomycin is indicated in adult and pediatric patients for the treatment of septicemia, infective endocarditis, skin and skin structure infections, bone infections, and lower respiratory tract infections. Administered orally, vancomycin is indicated in adult and pediatric patients for the treatment of Clostridium difficile-associ...

Associated Conditions
Clostridium Difficile Associated Diarrhea (CDAD), Enterocolitis caused by Staphylococcus aureus, Infection caused by staphylococci, Severe Staphylococcal infection
Associated Therapies
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Clinical Trials
Related News

The Effects of Daptomycin and Cytokines Production in Comparison With Vancomycin

Phase 4
Completed
Conditions
Cellulitis
Interventions
Drug: Daptomycin
Drug: Vancomycin
First Posted Date
2012-06-22
Last Posted Date
2015-03-20
Lead Sponsor
Hospital Universitario Evangelico de Curitiba
Target Recruit Count
20
Registration Number
NCT01626560
Locations
🇧🇷

Hospital Universitário Evangelico de Curitiba, Curitiba, Parana, Brazil

A Study of CB-183,315 in Participants With Clostridium Difficile Associated Diarrhea (MK-4261-006)

First Posted Date
2012-05-15
Last Posted Date
2022-08-22
Lead Sponsor
Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Target Recruit Count
608
Registration Number
NCT01598311

Study of CB-183,315 in Participants With Clostridium Difficile Associated Diarrhea (MK-4261-005)

First Posted Date
2012-05-14
Last Posted Date
2019-07-23
Lead Sponsor
Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Target Recruit Count
606
Registration Number
NCT01597505

Evaluation of Patients With Methicillin-Resistant Staphylococcus Aureus Hospital-Acquired Pneumonia Treated With Linezolid or Vancomycin

First Posted Date
2012-03-23
Last Posted Date
2014-07-10
Lead Sponsor
Pfizer
Target Recruit Count
188
Registration Number
NCT01561469

Evaluation of Daptomycin for the Emergency Department Treatment of Complicated Skin and Skin Structure Infections

Phase 4
Completed
Conditions
Cellulitis
Skin Infections
Interventions
Drug: Vancomycin
Drug: Daptomycin
First Posted Date
2012-03-09
Last Posted Date
2014-08-01
Lead Sponsor
University of Cincinnati
Target Recruit Count
104
Registration Number
NCT01549613
Locations
🇺🇸

University of Cincinnati, Dept. of Emergency Medicine, Cincinnati, Ohio, United States

Pharmacokinetics of Vancomycin for Inhalation in Cystic Fibrosis

First Posted Date
2012-01-13
Last Posted Date
2022-01-12
Lead Sponsor
Case Western Reserve University
Registration Number
NCT01509339
Locations
🇺🇸

Rainbow Babies and Children's Hospital, Univeristy Hospitals Case Medical Center, Cleveland, Ohio, United States

Evaluation of Ceftaroline Fosamil Versus Vancomycin Plus Aztreonam in the Treatment of Patients With Skin Infections

First Posted Date
2011-12-26
Last Posted Date
2017-09-06
Lead Sponsor
Pfizer
Target Recruit Count
802
Registration Number
NCT01499277
Locations
🇺🇦

Research Site, Odesa, Ukraine

Daptomycin Versus Vancomycin in Participants With Skin Infections Due to MRSA

First Posted Date
2011-08-18
Last Posted Date
2018-09-05
Lead Sponsor
Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Target Recruit Count
250
Registration Number
NCT01419184

Cost Study of Linezolid Versus Vancomycin Among Previously Hospitalized Patients

First Posted Date
2011-06-01
Last Posted Date
2012-05-22
Lead Sponsor
Pfizer
Target Recruit Count
7260
Registration Number
NCT01363271

Intracolonic Vancomycin Therapy in Severe C. Diff Colitis

Not Applicable
Terminated
Conditions
Colitis
Interventions
Drug: Saline
Drug: Vancomycin
First Posted Date
2011-05-02
Last Posted Date
2017-03-29
Lead Sponsor
William Beaumont Hospitals
Target Recruit Count
2
Registration Number
NCT01346059
Locations
🇺🇸

William Beaumont Hospital, Royal Oak, Michigan, United States

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