Vancomycin
- Generic Name
- Vancomycin
- Brand Names
- Firvanq, Vancocin
- Drug Type
- Small Molecule
- Chemical Formula
- C66H75Cl2N9O24
- CAS Number
- 1404-90-6
- Unique Ingredient Identifier
- 6Q205EH1VU
- Background
Antibacterial obtained from Streptomyces orientalis. It is a glycopeptide related to ristocetin that inhibits bacterial cell wall assembly and is toxic to kidneys and the inner ear.
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- Indication
Administered intravenously, vancomycin is indicated in adult and pediatric patients for the treatment of septicemia, infective endocarditis, skin and skin structure infections, bone infections, and lower respiratory tract infections. Administered orally, vancomycin is indicated in adult and pediatric patients for the treatment of Clostridium difficile-associ...
- Associated Conditions
- Clostridium Difficile Associated Diarrhea (CDAD), Enterocolitis caused by Staphylococcus aureus, Infection caused by staphylococci, Severe Staphylococcal infection
- Associated Therapies
- -
Steady State Serum and Epithelial Lining Fluid (ELF) Antibiotics Concentrations Under Continous Infusion
- Conditions
- First Posted Date
- 2007-02-14
- Last Posted Date
- 2008-06-09
- Lead Sponsor
- University Hospital Tuebingen
- Target Recruit Count
- 40
- Registration Number
- NCT00435305
- Locations
- 🇩🇪
Universitäsklinikum Tübingen, Klinik für Anästhesiologie und Intensivmedizin, Tübingen, Germany
Efficacy and Safety of Daptomycin Versus Vancomycin or Teicoplanin for Treatment of Complicated Skin and Soft Tissue Infections
- Conditions
- Interventions
- First Posted Date
- 2007-02-02
- Last Posted Date
- 2012-07-16
- Lead Sponsor
- Novartis Pharmaceuticals
- Target Recruit Count
- 194
- Registration Number
- NCT00430937
Study of Daptomycin in Subjects Undergoing Surgery for Osteomyelitis Associated With an Infected Prosthetic Caused by Staphylococci
- Conditions
- Interventions
- First Posted Date
- 2007-01-30
- Last Posted Date
- 2018-01-31
- Target Recruit Count
- 75
- Registration Number
- NCT00428844
- Locations
- 🇺🇸
Dartmouth-Hitchcock Medical center, Lebanon, New Hampshire, United States
🇷🇺Federal Healthcare Institute "Novosibirsk Scientific Research Institute of Traumatology and Orthopedy Rosmeditechnology", Novosibirsk, Russian Federation
🇺🇸Gundersen Clinic, LTD, La Crosse, Wisconsin, United States
Cotrimoxazole Versus Vancomycin for Invasive Methicillin-resistant Staphylococcus Aureus Infections
- Conditions
- Interventions
- First Posted Date
- 2007-01-26
- Last Posted Date
- 2015-09-25
- Lead Sponsor
- Rabin Medical Center
- Target Recruit Count
- 252
- Registration Number
- NCT00427076
- Locations
- 🇮🇱
Rabin Medical Center; Beilinson Hospital and Davidoff Cancer Center, Petah Tikva, Israel
🇮🇱Rambam Health Care Campus, Haifa, Israel
Phase 2 Safety and Efficacy Study of Daptomycin in Complicated Skin and Skin Structure Infections
- Conditions
- First Posted Date
- 2007-01-25
- Last Posted Date
- 2010-09-14
- Target Recruit Count
- 100
- Registration Number
- NCT00426933
- Locations
- 🇺🇸
Idaho Falls Infectious Diseases, PLLC, Idaho Falls, Idaho, United States
Study of Nitazoxanide in the Treatment of Clostridium Difficile-associated Disease
- First Posted Date
- 2006-10-06
- Last Posted Date
- 2015-05-05
- Lead Sponsor
- Romark Laboratories L.C.
- Target Recruit Count
- 50
- Registration Number
- NCT00384527
- Locations
- 🇺🇸
Michael E. Debakey VAMC, Houston, Texas, United States
🇺🇸Bay Pines VAMC, Bay Pines, Florida, United States
🇺🇸John D. Dingell VAMC, Ann Arbor, Michigan, United States
Antibiotics for the Treatment of Ulcerative Colitis
- Conditions
- First Posted Date
- 2006-07-24
- Last Posted Date
- 2009-02-11
- Lead Sponsor
- University of Dundee
- Target Recruit Count
- 40
- Registration Number
- NCT00355602
- Locations
- 🇬🇧
Ninewells Hospital and Medical School, Dundee, Angus, United Kingdom
Vancomycin Or Trimethoprim/Sulfamethoxazole for Methicillin-resistant Staphylococcus Aureus Osteomyelitis
- Conditions
- Interventions
- First Posted Date
- 2006-05-11
- Last Posted Date
- 2023-04-11
- Lead Sponsor
- University of Washington
- Target Recruit Count
- 2
- Registration Number
- NCT00324922
- Locations
- 🇺🇸
University of Washington, Seattle, Washington, United States
Fidaxomicin Versus Vancomycin for the Treatment of Clostridium Difficile-Associated Diarrhea (CDAD) (MK-5119-018)
- Conditions
- Interventions
- First Posted Date
- 2006-04-17
- Last Posted Date
- 2017-04-21
- Target Recruit Count
- 629
- Registration Number
- NCT00314951
Vancomycin vs. Vancomycin Plus Gentamycin in Treatment of MRSA Infection
- Conditions
- First Posted Date
- 2006-03-20
- Last Posted Date
- 2009-09-28
- Lead Sponsor
- Michael E. DeBakey VA Medical Center
- Target Recruit Count
- 160
- Registration Number
- NCT00304811
- Locations
- 🇺🇸
Baylor College of Medicine, Houston, Texas, United States
🇺🇸Michael E. DeBakey Veterans Affairs Medical Center, Houston, Texas, United States
Drug Development Updates
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