Prasterone
- Generic Name
- Prasterone
- Brand Names
- Intrarosa
- Drug Type
- Small Molecule
- Chemical Formula
- C19H28O2
- CAS Number
- 53-43-0
- Unique Ingredient Identifier
- 459AG36T1B
- Background
Prasterone, also known as dehydroepiandrosterone (DHEA) is a major C19 steroid produced by the adrenal cortex. It is also produced in small quantities in the testis and the ovary. Dehydroepiandrosterone (DHEA) can be converted to testosterone; androstenedione; estradiol; and estrone. Most of DHEA is sulfated (dehydroepiandrosterone sulfate) before secretion....
- Indication
DHEA is taken as a supplement for a variety of unsubstantiated indications. The following indications have shown promise and are backed up by some scientific evidence: schizophrenia (DHEA may be more effective in women than men); improving the appearance of older people’s skin (taking DHEA by mouth seems to increase skin thickness and moisture, and decrease ...
- Associated Conditions
- Moderate Dyspareunia, Severe Dyspareunia
- Associated Therapies
- -
Dehydroepiandrosterone Versus Growth Hormone in Women Undergoing ICSI With Expected Poor Ovarian Response
- Conditions
- Interventions
- First Posted Date
- 2016-04-13
- Last Posted Date
- 2016-07-06
- Lead Sponsor
- Cairo University
- Target Recruit Count
- 210
- Registration Number
- NCT02736591
- Locations
- 🇪🇬
Cairo University Hospitals, Cairo, Egypt
🇪🇬Dar AlTeb subfertility centre, Cairo, Egypt
DHEA in Synovial Sarcoma Patients
- Conditions
- Interventions
- First Posted Date
- 2016-02-17
- Last Posted Date
- 2019-09-09
- Lead Sponsor
- Washington University School of Medicine
- Target Recruit Count
- 11
- Registration Number
- NCT02683148
- Locations
- 🇺🇸
Washington University School of Medicine, Saint Louis, Missouri, United States
DHEA Versus Placebo in Women With Poor Ovarian Response
- First Posted Date
- 2015-09-28
- Last Posted Date
- 2016-07-06
- Lead Sponsor
- Cairo University
- Target Recruit Count
- 440
- Registration Number
- NCT02561793
- Locations
- 🇪🇬
Dar AlTeb subfertility centre, Giza, Egypt
🇪🇬Cairo University Hospitals, Cairo, Egypt
Testosterone Gel in Poor Responders Undergoing IVF
- First Posted Date
- 2015-09-15
- Last Posted Date
- 2017-04-18
- Lead Sponsor
- Vietnam National University
- Registration Number
- NCT02549690
- Locations
- 🇻🇳
My Duc Hospital, Ho Chi Minh City, Ward 13. Tan Binh District, Vietnam
Effect of DHEA on Patients With Poor Ovarian Responds
- Conditions
- Interventions
- First Posted Date
- 2015-05-04
- Last Posted Date
- 2023-07-20
- Target Recruit Count
- 350
- Registration Number
- NCT02432248
- Locations
- 🇨🇳
The Affiliated Hospital of Inner Mongolia Medical University, Inner Mongolia, China
The Effect of a Higher Dose of Dehydroepiandrosterone (DHEA) Supplementation in Poor Responders
- First Posted Date
- 2015-02-06
- Last Posted Date
- 2015-11-17
- Lead Sponsor
- ShangHai Ji Ai Genetics & IVF Institute
- Target Recruit Count
- 50
- Registration Number
- NCT02357472
- Locations
- 🇨🇳
Ji Ai Genetics and IVF center, Shang Hai, Shanghai, China
Assess the Effect of Dehydroepiandrosterone (DHEA) or Other Androgenic Agents Over Markers of Ovarian Reserve
- Conditions
- Interventions
- First Posted Date
- 2014-10-20
- Last Posted Date
- 2019-05-29
- Lead Sponsor
- Laboratorios Andromaco S.A.
- Target Recruit Count
- 94
- Registration Number
- NCT02268032
- Locations
- 🇨🇱
Mother and Health Research Institute (IDIMI), Faculty of Medicine, University of Chile, Santiago, International, Chile
Does Dehydro Epiandrosterone (DHEA) Improve Pregnancy Rate in Women Undergoing IVF/ICSI With Expected Poor Ovarian Response?
- First Posted Date
- 2014-05-30
- Last Posted Date
- 2015-05-19
- Lead Sponsor
- Cairo University
- Target Recruit Count
- 140
- Registration Number
- NCT02151006
- Locations
- 🇪🇬
Dar AlTeb subfertility centre, Giza, Egypt
🇪🇬Cairo University Hospitals, Cairo, Egypt
Effect of Dehydroepiandrosterone Administration in Patients With Poor Ovarian Response According to the Bologna Criteria
- First Posted Date
- 2014-05-07
- Last Posted Date
- 2014-05-07
- Lead Sponsor
- Chinese Medical Association
- Target Recruit Count
- 386
- Registration Number
- NCT02132559
- Locations
- 🇨🇳
Reproductive Medicine Center, Tongji Hospital, Tongji Medicine College, Huazhong University of Science and Technology, Wuhan, Hubei, China
A Phase II Study Evaluating the Role of Androgen Receptors as Targets for Therapy of Pre-treated Post-menopausal Patients With ER/PgR-negative/AR-positive or ER and/or PgRpositive/ AR-positive Metastatic Breast Cancer (ARTT)
- First Posted Date
- 2013-12-04
- Last Posted Date
- 2016-09-29
- Target Recruit Count
- 20
- Registration Number
- NCT02000375
- Locations
- 🇮🇹
Oncologia medica PO Ravenna AUSL della Romagna, Ravenna, RA, Italy
🇮🇹Oncologia Medica PO Lugo, AUSL della Romagna, Lugo, RA, Italy
🇮🇹Oncologia medica , PO FAENZA, Ausl della Romagna, Faenza, RA, Italy
Drug Development Updates
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