Prasterone
- Generic Name
- Prasterone
- Brand Names
- Intrarosa
- Drug Type
- Small Molecule
- Chemical Formula
- C19H28O2
- CAS Number
- 53-43-0
- Unique Ingredient Identifier
- 459AG36T1B
- Background
Prasterone, also known as dehydroepiandrosterone (DHEA) is a major C19 steroid produced by the adrenal cortex. It is also produced in small quantities in the testis and the ovary. Dehydroepiandrosterone (DHEA) can be converted to testosterone; androstenedione; estradiol; and estrone. Most of DHEA is sulfated (dehydroepiandrosterone sulfate) before secretion....
- Indication
DHEA is taken as a supplement for a variety of unsubstantiated indications. The following indications have shown promise and are backed up by some scientific evidence: schizophrenia (DHEA may be more effective in women than men); improving the appearance of older people’s skin (taking DHEA by mouth seems to increase skin thickness and moisture, and decrease ...
- Associated Conditions
- Moderate Dyspareunia, Severe Dyspareunia
- Associated Therapies
- -
Dehydroepiandrosterone (DHEA) Intervention To Treat Ovarian Aging
- Conditions
- Interventions
- First Posted Date
- 2012-04-05
- Last Posted Date
- 2015-12-09
- Lead Sponsor
- University of Nottingham
- Target Recruit Count
- 60
- Registration Number
- NCT01572025
- Locations
- 🇬🇧
Nottingham University Research and Treatment Unit in Reproduction (NURTURE), Nottingham, Nottinghamshire, United Kingdom
Prasterone (Dehydroepiandrosterone) in Treating Postmenopausal Cancer Survivors With Vaginal Symptoms
- Conditions
- Interventions
- First Posted Date
- 2011-06-20
- Last Posted Date
- 2019-02-07
- Lead Sponsor
- Alliance for Clinical Trials in Oncology
- Target Recruit Count
- 464
- Registration Number
- NCT01376349
- Locations
- 🇺🇸
St. Mary - Corwin Regional Medical Center, Pueblo, Colorado, United States
🇺🇸Illinois CancerCare - Macomb, Macomb, Illinois, United States
🇺🇸Elkhart Clinic, LLC, Elkhart, Indiana, United States
Dehydroepiandrosterone (DHEA) Against Vaginal Atrophy
- First Posted Date
- 2011-05-24
- Last Posted Date
- 2017-06-12
- Lead Sponsor
- EndoCeutics Inc.
- Target Recruit Count
- 450
- Registration Number
- NCT01358760
- Locations
- 🇺🇸
EndoCeutics site # 66, Danbury, Connecticut, United States
🇺🇸EndoCeutics site # 27, Baltimore, Maryland, United States
🇺🇸EndoCeutics site # 15, Columbus, Ohio, United States
DHEA Against Vaginal Atrophy - Safety Study of 12 Months
- First Posted Date
- 2010-12-08
- Last Posted Date
- 2017-10-18
- Lead Sponsor
- EndoCeutics Inc.
- Target Recruit Count
- 530
- Registration Number
- NCT01256671
- Locations
- 🇺🇸
EndoCeutics site # 25, Lincoln, Nebraska, United States
🇺🇸EndoCeutics site # 09, West Jordan, Utah, United States
🇨🇦EndoCeutics site # 13, Calgary, Alberta, Canada
DHEA Against Vaginal Atrophy - 3-Month Efficacy Study
- First Posted Date
- 2010-12-08
- Last Posted Date
- 2017-06-26
- Lead Sponsor
- EndoCeutics Inc.
- Target Recruit Count
- 255
- Registration Number
- NCT01256684
- Locations
- 🇺🇸
EndoCeutics site # 21, Sacramento, California, United States
🇺🇸EndoCeutics site # 22, Kalamazoo, Michigan, United States
🇺🇸EndoCeutics site # 10, Meridian, Idaho, United States
The Use of DHEA in Women With Premature Ovarian Failure
- First Posted Date
- 2010-05-25
- Last Posted Date
- 2013-01-29
- Lead Sponsor
- Virginia Center for Reproductive Medicine
- Registration Number
- NCT01129947
- Locations
- 🇺🇸
Virginia Center for Reproductive Medicine, Reston, Virginia, United States
DHEA in Treating Women Undergoing Surgery for Stage I, Stage II, or Stage III Breast Cancer
- First Posted Date
- 2009-09-04
- Last Posted Date
- 2019-09-17
- Lead Sponsor
- Barbara Ann Karmanos Cancer Institute
- Target Recruit Count
- 1
- Registration Number
- NCT00972023
- Locations
- 🇺🇸
Barbara Ann Karmanos Cancer Institute, Detroit, Michigan, United States
Dehydroepiandrosterone (DHEA) Treatment in Women and Men Experiencing Hypoactive Sexual Desire Disorder
- Conditions
- Interventions
- First Posted Date
- 2009-06-09
- Last Posted Date
- 2009-12-01
- Lead Sponsor
- Tel-Aviv Sourasky Medical Center
- Target Recruit Count
- 50
- Registration Number
- NCT00916396
- Locations
- 🇮🇱
Tel Aviv Aviv Medical Center, Tel Aviv, Israel
Hypoglycemia Associated Autonomic Failure in Type 1 Diabetes Mellitus
- Conditions
- Interventions
- First Posted Date
- 2008-02-06
- Last Posted Date
- 2019-09-12
- Lead Sponsor
- University of Maryland, Baltimore
- Target Recruit Count
- 50
- Registration Number
- NCT00607646
- Locations
- 🇺🇸
University of Maryland, Baltimore, Baltimore, Maryland, United States
Dehydroepiandrosterone Substitution in Adolescent and Young Women With Central Adrenal Insufficiency
- Conditions
- Interventions
- First Posted Date
- 2007-12-18
- Last Posted Date
- 2007-12-18
- Lead Sponsor
- University Hospital Tuebingen
- Target Recruit Count
- 23
- Registration Number
- NCT00575341
- Locations
- 🇩🇪
Universitaetskinik für Kinder und Jugendliche, Erlangen, Bayern, Germany
🇩🇪Universitaetsklinik und Poliklinik für Kinder und Jungendliche, Leipzig, Sachsen, Germany
🇩🇪Universitaere Kinderklinik, Heidelberg, Baden-Wuerttemberg, Germany
Drug Development Updates
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