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JNJ-2113

Generic Name
JNJ-2113

A Study to Assess Efficacy and Safety of JNJ-77242113 Compared to Placebo and Ustekinumab in Participants With Moderate to Severe Plaque Psoriasis

Phase 3
Not yet recruiting
Conditions
Plaque Psoriasis
Interventions
Drug: Matching Placebo to Ustekinumab
Drug: Matching Placebo to JNJ-77242113
First Posted Date
2025-04-18
Last Posted Date
2025-04-18
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
675
Registration Number
NCT06934226

A Study to Evaluate the Efficacy and Safety of JNJ-77242113 (Icotrokinra) in Biologic-naïve Participants With Active Psoriatic Arthritis

Phase 3
Recruiting
Conditions
Arthritis, Psoriatic
Interventions
Drug: Placebo
Drug: Active reference comparator
First Posted Date
2025-03-17
Last Posted Date
2025-04-27
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
540
Registration Number
NCT06878404
Locations
🇯🇵

Sasebo Chuo Hospital, Sasebo, Japan

🇪🇸

Corporacio Sanitari Parc Tauli, Sabadell, Spain

🇪🇸

Hosp. Univ. Marques de Valdecilla, Santander, Spain

and more 71 locations

A Study to Evaluate the Efficacy and Safety of Icotrokinra (JNJ-77242113) in Biologic-experienced Participants With Active Psoriatic Arthritis

Phase 3
Recruiting
Conditions
Arthritis, Psoriatic
Interventions
Drug: Placebo
First Posted Date
2025-02-04
Last Posted Date
2025-04-27
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
750
Registration Number
NCT06807424
Locations
🇭🇺

Betegapolo Irgalmas Rend Budai Irgalmasrendi Korhaz, Budapest, Hungary

🇭🇺

Qualiclinic Kft, Budapest, Hungary

🇭🇺

MAV Korhaz es Rendelointezet, Szolnok, Hungary

and more 72 locations

A Study of JNJ-77242113 for the Treatment of Participants With Generalized Pustular Psoriasis or Erythrodermic Psoriasis

Phase 3
Active, not recruiting
Conditions
Erythrodermic Psoriasis
Generalized Pustular Psoriasis
Interventions
First Posted Date
2024-03-06
Last Posted Date
2025-04-27
Lead Sponsor
Janssen Pharmaceutical K.K.
Target Recruit Count
19
Registration Number
NCT06295692
Locations
🇯🇵

JR Sapporo Hospital, Hokkaido, Japan

🇯🇵

Ichinomiya Municipal Hospital, Ichinomiya, Japan

🇯🇵

Teikyo University Hospital, Itabashi Ku, Japan

and more 9 locations

A Study of JNJ-77242113 for the Treatment of Participants With Moderate to Severe Plaque Psoriasis (ICONIC-ADVANCE 2)

Phase 3
Active, not recruiting
Conditions
Plaque Psoriasis
Interventions
First Posted Date
2024-01-24
Last Posted Date
2025-04-27
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
731
Registration Number
NCT06220604
Locations
🇩🇪

Universitatsmedizin der Johannes Gutenberg Universitat Mainz, Mainz, Germany

🇵🇱

WroMedica I Bielicka A Strzalkowska s c, Wroclaw, Poland

🇺🇸

Essential Medical Research, Tulsa, Oklahoma, United States

and more 123 locations

A Study of JNJ-77242113 for the Treatment of Participants With Moderate to Severe Plaque Psoriasis

Phase 3
Active, not recruiting
Conditions
Plaque Psoriasis
Interventions
First Posted Date
2023-11-22
Last Posted Date
2025-04-25
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
774
Registration Number
NCT06143878
Locations
🇭🇺

SZTE AOK Szent-Gyorgyi Albert Klinikai Kozpont, Borgyogyaszati és Allergologiai Klinika, Szeged, Hungary

🇭🇺

Allergo-Derm Bakos Kft., Szolnok, Hungary

🇭🇺

Medmare Egeszsegugyi Es Szolgaltato Bt., Veszprem, Hungary

and more 157 locations

A Study of JNJ-77242113 for the Treatment of Participants With Plaque Psoriasis Involving Special Areas (Scalp, Genital, and/or Palms of the Hands and the Soles of the Feet)

Phase 3
Active, not recruiting
Conditions
Plaque Psoriasis
Interventions
Drug: Placebo
First Posted Date
2023-10-23
Last Posted Date
2025-04-04
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
311
Registration Number
NCT06095102
Locations
🇺🇸

California Dermatology & Clinical Research Institute, Encinitas, California, United States

🇺🇸

Forcare Clinical Research Inc, Tampa, Florida, United States

🇺🇸

Hamilton Research LLC, Alpharetta, Georgia, United States

and more 86 locations

A Study of JNJ-77242113 in Adolescent and Adult Participants With Moderate to Severe Plaque Psoriasis

Phase 3
Active, not recruiting
Conditions
Plaque Psoriasis
Interventions
Drug: Placebo
First Posted Date
2023-10-23
Last Posted Date
2025-04-27
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
684
Registration Number
NCT06095115
Locations
🇺🇸

Medical Dermatology Specialists, Phoenix, Arizona, United States

🇺🇸

Johnson Dermatology, Fort Smith, Arkansas, United States

🇺🇸

First OC Dermatology, Fountain Valley, California, United States

and more 164 locations

A Study of JNJ-77242113 in Participants With Moderately to Severely Active Ulcerative Colitis

Phase 2
Active, not recruiting
Conditions
Colitis, Ulcerative
Interventions
Drug: Placebo
First Posted Date
2023-09-21
Last Posted Date
2025-04-27
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
252
Registration Number
NCT06049017
Locations
🇺🇸

Clinnova Research, Anaheim, California, United States

🇺🇸

Peak Gastroenterology Associates, Colorado Springs, Colorado, United States

🇺🇸

I.H.S. Health. LLC, Kissimmee, Florida, United States

and more 172 locations

A Study of JNJ-77242113 Following Oral Administration in Healthy Chinese Adult Participants

Phase 1
Completed
Conditions
Healthy
Interventions
First Posted Date
2023-01-30
Last Posted Date
2023-06-05
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
30
Registration Number
NCT05703841
Locations
🇨🇳

Peking University Third Hospital, Beijing, China

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