Levetiracetam
- Generic Name
- Levetiracetam
- Brand Names
- Elepsia, Keppra, Matever, Roweepra, Spritam, Levetiracetam Accord, Levetiracetam Teva, Levetiracetam Actavis, Levetiracetam ratiopharm, Levetiracetam Sun, Levetiracetam Actavis Group, Levetiracetam Hospira
- Drug Type
- Small Molecule
- Chemical Formula
- C8H14N2O2
- CAS Number
- 102767-28-2
- Unique Ingredient Identifier
- 44YRR34555
- Background
Levetiracetam is a drug within the pyrrolidine class that is used to treat various types of seizures stemming from epileptic disorders. It was first approved for use in the United States in 1999 and is structurally and mechanistically unrelated to other anti-epileptic drugs (AEDs). Levetiracetam possesses a wide therapeutic index and little-to-no potential t...
- Indication
Levetiracetam is indicated as an adjunctive therapy in the treatment of partial onset seizures in epileptic patients who are one month of age and older. Additionally, it is indicated as an adjunct in the treatment of myoclonic seizures in patients with juvenile myoclonic epilepsy who are 12 years of age and older, and in primary generalized tonic-clonic seiz...
- Associated Conditions
- Epilepsies, Generalized Tonic-Clonic Seizures, Partial-Onset Seizures, Myoclonic seizures
- Associated Therapies
- -
Levetiracetam or Pregabalin in Treating Seizures in Patients Undergoing Chemotherapy and/or Radiation Therapy For Primary Brain Tumors
- Conditions
- Interventions
- First Posted Date
- 2008-03-06
- Last Posted Date
- 2013-05-22
- Lead Sponsor
- Dr Andrea Rossetti
- Target Recruit Count
- 52
- Registration Number
- NCT00629889
- Locations
- 🇨🇭
Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
🇨🇭USZ, Zürich, Switzerland
Efficacy of Keppra in Acute Alcohol Related Seizure Control--A Pilot Study
- First Posted Date
- 2008-02-29
- Last Posted Date
- 2018-06-07
- Lead Sponsor
- Medical University of South Carolina
- Registration Number
- NCT00627133
- Locations
- 🇺🇸
Medical University of South Carolina, Charleston, South Carolina, United States
Efficacy of Levetiracetam in Essential Tremor
- First Posted Date
- 2008-02-21
- Last Posted Date
- 2009-04-17
- Target Recruit Count
- 10
- Registration Number
- NCT00620165
- Locations
- 🇺🇸
VA Long Beach Healthcare System, Long Beach, California, United States
Assess Safety and Efficacy of Levetiracetam(LEV;Keppra)for Seizure Prevention
- Conditions
- Interventions
- First Posted Date
- 2008-02-20
- Last Posted Date
- 2014-04-07
- Lead Sponsor
- University of Cincinnati
- Target Recruit Count
- 52
- Registration Number
- NCT00618436
- Locations
- 🇺🇸
University of Cincinnati Hospital, Cincinnati, Ohio, United States
Efficacy and Tolerability of Levetiracetam Add-On Treatment in Refractory Pediatric Patients With Partial Onset Seizures
- First Posted Date
- 2008-02-14
- Last Posted Date
- 2020-07-30
- Lead Sponsor
- UCB Pharma
- Target Recruit Count
- 216
- Registration Number
- NCT00615615
Study to Assess the Efficacy and Safety of Levetiracetam for the Treatment of Social Anxiety Disorder (Generalized Type)
- Conditions
- First Posted Date
- 2008-02-12
- Last Posted Date
- 2013-11-26
- Lead Sponsor
- UCB Pharma
- Target Recruit Count
- 217
- Registration Number
- NCT00612859
Premenstrual Dysphoric Disorder and Antiepileptic Drugs
- Conditions
- Interventions
- First Posted Date
- 2008-02-11
- Last Posted Date
- 2018-10-26
- Lead Sponsor
- Beth Israel Deaconess Medical Center
- Target Recruit Count
- 80
- Registration Number
- NCT00612235
- Locations
- 🇺🇸
Brigham and Women's Hospital, Boston, Massachusetts, United States
🇺🇸Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States
🇺🇸Newton-Wellesley Hospital, Newton, Massachusetts, United States
Safety and Tolerability of Levetiracetam Intravenous 15 Minute Infusion in Subjects Suffering From Partial Onset Seizures
- Conditions
- First Posted Date
- 2008-02-08
- Last Posted Date
- 2013-12-06
- Lead Sponsor
- UCB Pharma
- Target Recruit Count
- 25
- Registration Number
- NCT00610454
Bridging Study of L059 (Levetiracetam) in Patients With Epilepsy by Double Blind Method
- Conditions
- First Posted Date
- 2008-01-25
- Last Posted Date
- 2013-09-17
- Lead Sponsor
- UCB Pharma
- Target Recruit Count
- 216
- Registration Number
- NCT00600509
Levetiracetam (Keppra) Tolerability in Cocaine Abusing Methadone-maintained Patients.
- First Posted Date
- 2008-01-14
- Last Posted Date
- 2017-01-12
- Lead Sponsor
- Yale University
- Target Recruit Count
- 15
- Registration Number
- NCT00593125
- Locations
- 🇺🇸
VA CT Healthcare System, West Haven, Connecticut, United States
Drug Development Updates
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