Lansoprazole
- Generic Name
- Lansoprazole
- Brand Names
- Prevacid, Prevpac
- Drug Type
- Small Molecule
- Chemical Formula
- C16H14F3N3O2S
- CAS Number
- 103577-45-3
- Unique Ingredient Identifier
- 0K5C5T2QPG
- Background
Lansoprazole marketed under the brand Prevacid, is a proton pump inhibitor (PPI) and is structurally classified as a substituted benzimidazole. It reduces gastric acid secretion by targeting gastric H,K-ATPase pumps and is thus effective at promoting healing in ulcerative diseases, and treating gastroesophageal reflux disease (GERD) along with other patholog...
- Indication
Lansoprazole is used to reduce gastric acid secretion and is approved for short term treatment of active gastric ulcers, active duodenal ulcers, erosive reflux oesophagitis, symptomatic gastroesophageal reflux disease, and non-steroidal anti-inflammatory drug (NSAID) induced gastric and duodenal ulcers. It may be used in the maintenance and healing of sever...
- Associated Conditions
- Duodenal Ulcer, Erosive Esophagitis, Helicobacter Pylori Infection, Symptomatic Gastroesophageal Reflux Disease (sGERD), Ulcer Healing, Zollinger-Ellison Syndrome, Active Duodenal ulcer, Develop NSAID-induced gastric ulcers, Hypersecretory conditions, Maintenance of healing Erosive esophagitis
- Associated Therapies
- -
Proton Pump Inhibitors and Risk of Community-acquired Pneumonia
- Conditions
- Interventions
- First Posted Date
- 2015-09-22
- Last Posted Date
- 2015-09-22
- Target Recruit Count
- 4238504
- Registration Number
- NCT02555852
- Locations
- 🇨🇦
Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, Quebec, Canada
Efficacy and Safety of Oral Once-Daily Vonoprazan (TAK-438) in Participants With Erosive Esophagitis
- Conditions
- Interventions
- First Posted Date
- 2015-03-17
- Last Posted Date
- 2019-06-03
- Lead Sponsor
- Takeda
- Target Recruit Count
- 481
- Registration Number
- NCT02388724
- Locations
- 🇰🇷
Kangbuk Samsung Hospital, Seoul, Korea, Republic of
🇰🇷Asan Medical Center, Seoul, Korea, Republic of
🇰🇷The Catholic University of Korea, Seoul St. Marys Hospital, Seoul, Korea, Republic of
Efficacy and Safety of Vonoprazan Compared to Lansoprazole in the Maintenance Treatment of Erosive Esophagitis
- Conditions
- Interventions
- First Posted Date
- 2015-03-17
- Last Posted Date
- 2020-02-21
- Lead Sponsor
- Takeda
- Target Recruit Count
- 703
- Registration Number
- NCT02388737
- Locations
- 🇲🇾
University Malaya Medical Centre, Kuala Lumpur, Malaysia
🇨🇳Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan
🇨🇳Taipei Medical University Hospital, Taipei City, Taiwan
Open-label PK Study to Evaluate Lansoprazole and Neratinib in Healthy Subjects
- First Posted Date
- 2015-01-08
- Last Posted Date
- 2016-05-11
- Lead Sponsor
- Puma Biotechnology, Inc.
- Target Recruit Count
- 15
- Registration Number
- NCT02334501
- Locations
- 🇺🇸
Celerion, Tempe, Arizona, United States
The Relationship Between Gastroesophageal Reflux and Pediatric Rhinitis: Significance of Pale/Blue Colored Turbinate
- First Posted Date
- 2014-10-29
- Last Posted Date
- 2014-10-29
- Lead Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
- Target Recruit Count
- 98
- Registration Number
- NCT02278081
Pharmacokinetics of Dipyridamole Administered as Aggrenox® (Dipyridamole Extended Release Plus Aspirin) Capsule Versus Dipyridamole Immediate Release Plus Aspirin Following Alteration of Stomach pH
- Conditions
- Interventions
- First Posted Date
- 2014-09-29
- Last Posted Date
- 2014-09-29
- Lead Sponsor
- Boehringer Ingelheim
- Target Recruit Count
- 31
- Registration Number
- NCT02251184
High Dose Amoxicillin Versus Tetracycline as Second-line Treatment of Resistant Helicobacter Pylori Infection
- Conditions
- Interventions
- First Posted Date
- 2014-06-26
- Last Posted Date
- 2016-03-01
- Lead Sponsor
- Shanghai Jiao Tong University School of Medicine
- Target Recruit Count
- 312
- Registration Number
- NCT02175927
- Locations
- 🇨🇳
Shanghai Renji Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai, Shanghai, China
Amoxicillin/Metronidazole Based Quadruple Therapy for Helicobacter Pylori Eradication
- Conditions
- Interventions
- First Posted Date
- 2014-06-26
- Last Posted Date
- 2015-02-03
- Lead Sponsor
- Shanghai Jiao Tong University School of Medicine
- Target Recruit Count
- 215
- Registration Number
- NCT02175901
- Locations
- 🇨🇳
Shanghai Renji Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai, Shanghai, China
Takepron Intravenous 30 mg Specified Drug-use Survey [Acute Stress Ulcer and Acute Gastric Mucosal Lesions]
- Conditions
- Interventions
- First Posted Date
- 2014-06-23
- Last Posted Date
- 2016-03-08
- Lead Sponsor
- Takeda
- Target Recruit Count
- 63
- Registration Number
- NCT02170207
Lansoprazole Intravenous 30 mg Specified Drug-use Survey [Hemostatic Effect/Rebleeding Rate]
- Conditions
- Interventions
- First Posted Date
- 2014-05-30
- Last Posted Date
- 2016-02-23
- Lead Sponsor
- Takeda
- Target Recruit Count
- 1120
- Registration Number
- NCT02151786
Drug Development Updates
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