Phenylephrine
- Generic Name
- Phenylephrine
- Brand Names
- 4-way, Advil Congestion Relief, Advil Sinus Congestion and Pain, Ala-hist PE, Allerest PE, Benadryl-D Allergy and Sinus, Biorphen, Cyclomydril, Dayquil Sinex, Deconex, Despec Reformulated Jun 2008, Dimetapp Nighttime Cold & Congestion, Diphen, Entex Lq, Gilphex, Histex Ac, Immphentiv, Little Noses Decongestant, M-end PE, Mucinex Stuffy Nose & Cold, Mydcombi, Mydfrin, Nasopen PE, Neo-synephrine, Omidria, Poly Hist Forte Reformulated Nov 2013, Preparation H Cooling Gel, Preparation H Cream, Preparation H Reformulated Jun 2013, Refenesen PE, Rescon-GG, Rymed-D, Soframycin, Sudafed PE, Sudafed PE Children's Cold & Cough, Sudafed PE Children's Nasal Decongestant, Sudafed PE Head Congestion Plus Pain, Sudafed PE Sinus Headache, Sudo-tab, Sudogest PE, Triaminic Day Time Cold & Cough, Triaminic Night Time Cold & Cough, Vazculep, Wal-profen Congestion Relief and Pain
- Drug Type
- Small Molecule
- Chemical Formula
- C9H13NO2
- CAS Number
- 59-42-7
- Unique Ingredient Identifier
- 1WS297W6MV
- Background
Phenylephrine is an alpha-1 adrenergic receptor agonist used to treat hypotension, dilate the pupil, and induce local vasoconstriction. The action of phenylephrine, or neo-synephrine, was first described in literature in the 1930s.
Phenylephrine was granted FDA approval in 1939.
- Indication
Phenylephrine is available in various drug formulations, which have different indications. Phenylephrine injections are indicated to treat hypotension caused by shock or anesthesia. The ophthalmic formulation is indicated to induce mydriasis and conjunctival vasoconstriction. The intranasal formulation is used to treat congestion, and a topical formulation ...
- Associated Conditions
- Allergic Conjunctivitis (AC), Allergic Rhinitis (AR), Allergy to Tree Pollen, Anorectal discomfort, Cold, Common Cold, Congestion of the Conjunctivas, Cough, Cough caused by Common Cold, Eye allergy, Eye redness, Fever, Flu caused by Influenza, Haemorrhoids, Headache, Headache caused by Allergies, Headache caused by Common Cold, Headache caused by Pollen Allergy, Hypotension, Irritative cough, Itching of the nose, Itching of the throat, Laryngotracheitis, Nasal Congestion, Nose discomfort, Ocular Inflammation, Ocular Irritation, Paroxysmal Supraventricular Tachycardia (PSVT), Respiratory tract congestion, Respiratory tract irritation, Rhinopharyngitis, Rhinorrhoea, Seasonal Allergies, Sinus Congestion, Sinus pressure, Sinusitis, Sneezing, Sore Throat, Tracheobronchitis, Upper respiratory tract hypersensitivity reaction, site unspecified, Vasomotor Rhinitis, Aching caused by Flu caused by Influenza, Bronchial congestion, Cold or flu syndrome, Itchy throat, Minor aches and pains, Vascular failure, Watery itchy eyes
- Associated Therapies
- Airway secretion clearance therapy, Mydriasis, Antihistamine, Vasoconstrictor in regional analgesia therapy
Ephedrine Versus Phenylephrine for Spinal Block - Related Hypotension in Cesarean Delivery
Not yet recruiting
- Conditions
- Interventions
- First Posted Date
- 2024-12-19
- Last Posted Date
- 2024-12-19
- Lead Sponsor
- Centre of Postgraduate Medical Education
- Target Recruit Count
- 80
- Registration Number
- NCT06741410
- Locations
- 🇵🇱
Centre of Postgraduate Medical Education,Department of Anesthesia and Intensive Care, Warsaw, Poland
Clinical Study of DA-001 As a Treatment for Telogen Effluvium
Phase 3
Not yet recruiting
- Conditions
- Interventions
- First Posted Date
- 2024-10-18
- Last Posted Date
- 2024-12-19
- Lead Sponsor
- Applied Biology, Inc.
- Target Recruit Count
- 480
- Registration Number
- NCT06648850
Norepinephrine and Phenylephrine for Spinal Anesthesia-induced Hypotension.
Not Applicable
Not yet recruiting
- Conditions
- Interventions
- First Posted Date
- 2024-07-18
- Last Posted Date
- 2024-07-18
- Lead Sponsor
- General Hospital of Ningxia Medical University
- Target Recruit Count
- 2000
- Registration Number
- NCT06508359
The Contractile Response of the Thoracic Aorta to Vasoactive Substances
Not yet recruiting
- Conditions
- First Posted Date
- 2024-04-19
- Last Posted Date
- 2024-04-24
- Lead Sponsor
- Catharina Ziekenhuis Eindhoven
- Target Recruit Count
- 98
- Registration Number
- NCT06374836
- Locations
- 🇳🇱
Catharina hospital, Eindhoven, Noord-Brabant, Netherlands
Effect of Ephedrine, Phenylepinephrine, and Norepinephrine on Myometrial Contractility in Pregnant People With Type II and Gestational Diabetes During Cesarean Section: An In-vitro Study
Not Applicable
Recruiting
- Conditions
- Interventions
- First Posted Date
- 2024-02-29
- Last Posted Date
- 2024-04-12
- Target Recruit Count
- 24
- Registration Number
- NCT06285396
- Locations
- 🇨🇦
Mount Sinai Hospital, Toronto, Ontario, Canada
Tachycardia as an Indication for Prophylactic Phenylephrine Injection in Caesarean Section Under Spinal Anesthesia; an Observational Study
Recruiting
- Conditions
- First Posted Date
- 2024-01-24
- Last Posted Date
- 2024-01-24
- Lead Sponsor
- Ain Shams University
- Target Recruit Count
- 80
- Registration Number
- NCT06220942
- Locations
- 🇪🇬
maha sadek El Derh, Cairo, Heliopolis, Egypt
ED90 of Norepinephrine and Phenylephrine Boluses Under Intensive Treatment in Preeclamptic Patients
Not Applicable
Not yet recruiting
- Conditions
- Interventions
- First Posted Date
- 2023-12-06
- Last Posted Date
- 2023-12-06
- Lead Sponsor
- General Hospital of Ningxia Medical University
- Target Recruit Count
- 80
- Registration Number
- NCT06158035
ED90 of Norepinephrine and Phenylephrine Infusions Under Intensive Treatment in Preeclamptic Patients
Not Applicable
Recruiting
- Conditions
- Interventions
- First Posted Date
- 2023-12-06
- Last Posted Date
- 2024-12-04
- Lead Sponsor
- General Hospital of Ningxia Medical University
- Target Recruit Count
- 80
- Registration Number
- NCT06158022
- Locations
- 🇨🇳
General hospital of Ningxia University, Yinchuan, Ningxia, China
ED90 of Norepinephrine and Phenylephrine Boluses Under Intensive Treatment
Not Applicable
Not yet recruiting
- Conditions
- Interventions
- First Posted Date
- 2023-12-06
- Last Posted Date
- 2023-12-06
- Lead Sponsor
- General Hospital of Ningxia Medical University
- Target Recruit Count
- 80
- Registration Number
- NCT06158009
ED90 of Norepinephrine and Phenylephrine Infusions Under Intensive Treatment
Not Applicable
Not yet recruiting
- Conditions
- Interventions
- First Posted Date
- 2023-12-06
- Last Posted Date
- 2023-12-06
- Lead Sponsor
- General Hospital of Ningxia Medical University
- Target Recruit Count
- 80
- Registration Number
- NCT06158048
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