Tetracycline
- Generic Name
- Tetracycline
- Brand Names
- Pylera, Sumycin
- Drug Type
- Small Molecule
- Chemical Formula
- C22H24N2O8
- CAS Number
- 60-54-8
- Unique Ingredient Identifier
- F8VB5M810T
- Background
Tetracycline is a broad spectrum polyketide antibiotic produced by the Streptomyces genus of Actinobacteria. It exerts a bacteriostatic effect on bacteria by binding reversible to the bacterial 30S ribosomal subunit and blocking incoming aminoacyl tRNA from binding to the ribosome acceptor site. It also binds to some extent to the bacterial 50S ribosomal sub...
- Indication
Used to treat bacterial infections such as Rocky Mountain spotted fever, typhus fever, tick fevers, Q fever, rickettsialpox and Brill-Zinsser disease. May be used to treat infections caused by Chlamydiae spp., B. burgdorferi (Lyme disease), and upper respiratory infections caused by typical (S. pneumoniae, H. influenzae, and M. catarrhalis) and atypical orga...
- Associated Conditions
- Acinetobacter Infections, Actinomycosis, Anthrax, Bacterial Infections, Bartonellosis, Brucellosis, Campylobacter Infection, Chancroid, Chlamydial Infections, Cholera (Disorder), Clostridium Infections, Conjunctivitis, Inclusion, Cystitis, Endometritis, Entamoebic histolytica infection, Escherichia infections, Granuloma Inguinale, Helicobacter Pylori Infection, Infection, Infection, Bacteroides, Klebsiella Infections, Listeria infection, Lower respiratory tract infection bacterial, Lymphogranuloma Venereum, Necrotizing ulcerative gingivostomatitis, Neisseria Gonorrhoeae Infection, Nephritis, Ornithosis, Plague, Prostatitis, Psittacosis, Q Fever, Relapsing Fever, Rickettsialpox, Rocky Mountain Spotted Fever, Rosacea, Severe Acne, Shigella Infection, Skin Infections caused by Staphylococcus Aureus, Skin and Subcutaneous Tissue Bacterial Infections, Syphilis, Trachoma, Tularemia, Typhus, Upper respiratory tract infection bacterial, Urinary Tract Infection, Yaws, Grade 1, grade 2, grade 3, grade 4 Urinary Tract Infection
- Associated Therapies
- -
Study to Evaluate the Efficacy of Tetracycline in Epidermolysis Bullosa
- Conditions
- First Posted Date
- 2006-06-13
- Last Posted Date
- 2020-10-28
- Lead Sponsor
- Rambam Health Care Campus
- Registration Number
- NCT00336154
Tetracycline in Preventing Skin Rash in Patients Who Are Receiving Drugs Such as Gefitinib and Cetuximab for Cancer
- Conditions
- Interventions
- First Posted Date
- 2004-09-09
- Last Posted Date
- 2017-03-16
- Lead Sponsor
- Alliance for Clinical Trials in Oncology
- Target Recruit Count
- 130
- Registration Number
- NCT00091247
- Locations
- 🇺🇸
St. Luke's Hospital, Maumee, Ohio, United States
🇺🇸Fredericksburg Oncology, Incorporated, Fredericksburg, Virginia, United States
🇺🇸Saint Anthony Memorial Health Centers, Michigan City, Indiana, United States
Antibiotic Therapy in Treating Patients With Low Grade Gastric Lymphoma
- Conditions
- First Posted Date
- 2004-08-24
- Last Posted Date
- 2012-07-02
- Target Recruit Count
- 96
- Registration Number
- NCT00003151
- Locations
- 🇬🇧
Clatterbridge Centre for Oncology NHS Trust, Merseyside, England, United Kingdom
🇬🇧Royal United Hospital, Bath, England, United Kingdom
🇬🇧Royal Free Hospital, Hampstead, London, England, United Kingdom
Antibiotic Therapy and Antacids in Patients With Malt Lymphoma of the Stomach
- Conditions
- Interventions
- First Posted Date
- 2004-06-10
- Last Posted Date
- 2018-10-24
- Lead Sponsor
- M.D. Anderson Cancer Center
- Target Recruit Count
- 5
- Registration Number
- NCT00002682
- Locations
- 🇺🇸
University of Texas - MD Anderson Cancer Center, Houston, Texas, United States
🇺🇸MD Anderson Cancer Center Orlando, Orlando, Florida, United States
Drug Development Updates
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